364595-94-8Relevant academic research and scientific papers
Aza-Michael reaction promoted by aqueous sodium carbonate solution
Tang, Xiao-Ji,Yan, Zhao-Lei,Chen, Wen-Liang,Gao, Ya-Ru,Mao, Shuai,Zhang, Yan-Lei,Wang, Yong-Qiang
, p. 2669 - 2673 (2013)
A general and efficient aza-Michael reaction promoted by aqueous sodium carbonate solution has been developed. The reaction has complete mono-alkylation selectivity and proceeds with complete chirality retention for chiral amino esters. With a broad substrate scope, a well-common catalyst and simple operation, the catalytic approach provides a facile, practicable, economical, and environmentally benign method for the synthesis of β-amino carbonyl compounds.
