36469-01-9 Usage
General Description
2-methyl-2-pyridin-2-yl-indene-1,3-dione is a chemical compound with a molecular formula C17H11NO2. It is an indane-based organic compound that contains a pyridine ring and a methyl group. It is commonly used in the synthesis and development of pharmaceuticals and agrochemicals. 2-methyl-2-pyridin-2-yl-indene-1,3-dione has been studied for its potential biological activities, including its antiviral, antibacterial, and antifungal properties. Additionally, it has been investigated for its potential use in the treatment of cancer and various other diseases. The unique structure and reactivity of 2-methyl-2-pyridin-2-yl-indene-1,3-dione make it a valuable compound for research and development in the fields of medicinal chemistry and chemical biology.
Check Digit Verification of cas no
The CAS Registry Mumber 36469-01-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,6,4,6 and 9 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 36469-01:
(7*3)+(6*6)+(5*4)+(4*6)+(3*9)+(2*0)+(1*1)=129
129 % 10 = 9
So 36469-01-9 is a valid CAS Registry Number.
InChI:InChI=1/C15H11NO2/c1-15(12-8-4-5-9-16-12)13(17)10-6-2-3-7-11(10)14(15)18/h2-9H,1H3
36469-01-9Relevant articles and documents
Synthesis and pharmacological evaluation of 2-(2 and 4- pyridinyl)indane-1,3-diones and structuraly related compounds exerting potential anti-inflammatory and antitumoral activities
Robert-Piessard,Leblois,Courant,Baut,Petit
, p. 160 - 168 (2007/10/03)
Our on going work in the series of enamido-diketones issued from 2- azaarylindane-1,3-diones led us to synthesize and experiment N and C2- substituted derivatives of 2-(2 and 4-pyridinyl)indane-1,3-diones as well as of structurally related compounds resulting from the replacement of pyridine by quinoline and benzimidazole. Pharmacological evaluation of their anti- inflammatory activity (by inhibition of carrageenan foot edema) and their anticoagulant activity (by prothombin assay) led to the conclusion of the possibility of achieving a selective antiinflammatory effect. It has been previously established that anticoagulants are liable to exert a protective effect in the development of cancer metastasis. Nevertheless none of the six experimented 2-(pyridin-2-yl)indane-1,3-diones extended survival time of mice treated by P388 lymphocytic leukemia.