364765-26-4

Upstream product

• 10147-11-2 propargyl benzene 
• 591-31-1 3-methoxy-benzaldehyde 

Downstream Products

• 364765-28-6 1-(3-methoxyphenyl)-4-phenyl-2-butyn-1-one 
• 1266366-23-7 2,3-diiodo-1-(3-methoxyphenyl)-1,4-dihydronaphthalene 

Relevant academic research and scientific papers

Palladium-catalyzed tandem dimerization and cyclization of acetylenic ketones: A convenient method for 3,3′-bifurans using PdCl2(PPh3)2

Alkynones undergo tandem dimerization and cyclization in the presence of PdCl2(PPh3)2 and triethylamine in tetrahydrofuran at room temperature to give 3,3′-bifurans predominantly. Other palladium catalysts while under similar conditions, by rearrangement, lead to 2,5-disubstituted furans. This distinguished property of PdCl2(PPh3)2 has been attributed to the involvement of hydridopalladium halide. This method provides a simpler route to a variety of furans and a regioselective synthesis of polysubstituted 3,3′-bifurans using easily accessible acetylenic ketones.

Electrophilic carbocyclization of aryl propargylic alcohols: A facile synthesis of diiodinated carbocycles and heterocycles

Diiodinated carbocycles and oxygen heterocycles can be readily synthesized by electrophilic carbocyclization of aryl propargylic alcohols in moderate to good yields under mild conditions. The resulting diiodide can be further exploited by subsequent oxidi