364802-14-2

Upstream product

• 364802-09-5 N-(2-azido-benzyl)-N-(1-phenyl-ethyl)-acrylamide 
• 260352-56-5 N-(2-amino-benzyl)-N-(1-phenyl-ethyl)-acrylamide 
• 364802-10-8 (S)-5-((S)-1-Phenyl-ethyl)-3,3a,5,6-tetrahydro-1,2,5,10b-tetraaza-benzo[e]azulen-4-one 
• 364802-11-9 (R)-5-((S)-1-Phenyl-ethyl)-3,3a,5,6-tetrahydro-1,2,5,10b-tetraaza-benzo[e]azulen-4-one 

Relevant academic research and scientific papers

A one-step synthesis of enantiopure 2-substituted 4,5-dihydro-1,4-benzodiazepine-3-ones via intramolecular azide cycloaddition

Starting from the appropriate azides bearing the (S)-1-phenylethylamine and the l-alanine benzylester as chiral pendants, a facile and effective synthetic route to the title compounds in their enantiopure form was developed with excellent product yields o

Stereoselective intramolecular cycloadditions of homochiral N-alkenoyl aryl azides

Starting from the commercially available (S)-1-phenylethylamine and L-alanine benzylester, we synthesised the homochiral N-alkenoyl aryl azides 2a-2d. The intramolecular cycloaddition of unsubstituted 2a and 2b gave enantiopure 3,3a-dihydro-1,2,3-triazolo