365-34-4 Usage
Uses
Used in Organic Syntheses:
1-[2-(Trifluoromethyl)phenyl]hydrazine is used as an intermediate in organic syntheses for the production of a wide range of chemical compounds. Its unique structure allows it to participate in various chemical reactions, making it a valuable component in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used as a Fine Chemical Intermediate:
In the fine chemicals industry, 1-[2-(Trifluoromethyl)phenyl]hydrazine is utilized as a fine chemical intermediate. It plays a crucial role in the development of high-purity specialty chemicals that are used in various applications, including research, pharmaceuticals, and materials science.
Used as a Gas Chromatography (GC) Derivatizing Agent:
1-[2-(Trifluoromethyl)phenyl]hydrazine is employed as a GC derivatizing agent to improve the detection and analysis of certain compounds in gas chromatography. Its ability to react with a variety of functional groups makes it a useful tool for enhancing the sensitivity and selectivity of GC analysis.
Used as a Coupling Reagent:
In chemical synthesis, 1-[2-(Trifluoromethyl)phenyl]hydrazine serves as a coupling reagent, facilitating the formation of new chemical bonds between molecules. Its reactivity and stability make it a preferred choice for various coupling reactions in organic chemistry.
Used as an N-Protecting Agent:
1-[2-(Trifluoromethyl)phenyl]hydrazine is also used as an N-protecting agent in organic synthesis. It helps to temporarily mask or protect the nitrogen atom in amines and other nitrogen-containing compounds during chemical reactions, preventing unwanted side reactions and ensuring the desired product formation.
Check Digit Verification of cas no
The CAS Registry Mumber 365-34-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,6 and 5 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 365-34:
(5*3)+(4*6)+(3*5)+(2*3)+(1*4)=64
64 % 10 = 4
So 365-34-4 is a valid CAS Registry Number.
InChI:InChI=1/C7H7F3N2/c8-7(9,10)12-11-6-4-2-1-3-5-6/h1-5,11-12H
365-34-4Relevant academic research and scientific papers
Use of phenyl hydrazines for seed biostimulation or the treatment of lipoxygenase mediated seed deteriorations
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, (2008/06/13)
The present invention provides a method of treating certain deleterious conditions mediated by the action of lipoxygenases in mammals and seeds using certain phenyl hydrazines. Also provided is a method for seed biostimulation using these phenyl hydrazines.
Antiimplantation Agents: Part I - 1-Arylthiosemicarbazides
Nagarajan, K.,Talwalker, P.K.,Kulkarni, C.L.,Venkateswarlu, A.,Prabhu, S.S.,Nayak, G.V.
, p. 1243 - 1257 (2007/10/02)
Several 1-arylthiosemicarbazides, 2-arylhydrazinothiazolines and 2-arylhydrazinodihydrothiazines have been examined for their antiimplantation activity in rats.Among the active compounds, 4-methyl-1-(3,5-bistrifluoromethylphenyl)thiosemicarbazide (3, C 2696-Go) and the corresponding 4,4-dimethyl (47), ethyl (4), n-butyl (5) and allyl (6) derivatives completely inhibit implantation at doses 10, 3, 20, 20 and 30 mg/kg respectively.The 3,4-dichlorophenyl analogue (32) is effective at a dose of 30 mg/kg. 2-(3,5-Bistrifluoromethylphenyl)hydrazinothiazoline (51) and the corresponding dihydrothiazine (63) show a weaker activity.The biological profile of C 2696-Go has been investigated in detail.It appears to prevent implantation by its antiuterotropic activity and ability to inhibit desiduoma formation.
Process for producing 3-anilino-5-pyrazolones
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, (2008/06/13)
A process for producing a 3-anilino-5-pyrazolone which comprises reacting a β-anilino-β-alkoxy-acrylate with a hydrazine in the presence of a compound having a pKa of about 8 up to about 14.
