3652-88-8

Basic information

• Product Name: 4-chloro-9H-carbazole
• Synonyms: 4-chloro-9H-carbazole
• CAS NO: 3652-88-8
• Molecular Formula: C₁₂H₈ClN
• Molecular Weight: 201.65162
• Mol File: 3652-88-8.mol
• Article Data: 11

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-chloro-9H-carbazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloro-9H-carbazole(3652-88-8)
• EPA Substance Registry System: 4-chloro-9H-carbazole(3652-88-8)

Safety Data

• Hazardous Substances Data: 3652-88-8(Hazardous Substances Data)

Usage

General Description

4-chloro-9H-carbazole is a synthetic, halogenated compound of carbazole, which is an aromatic heterocyclic organic compound. It is relatively stable and is primarily used in the manufacture of other chemicals. The name 4-chloro-9H-carbazole refers to the specific atomic structure of the compound, with a chlorine atom attached at the fourth carbon in the carbazole ring. Its molecular formula is C12H8ClN and its molecular weight is 213.65 g/mol. It's important to handle this chemical with care as some studies suggest that carbazole derivatives may pose potential health and environmental risks. Experiments imply it may exhibit biological activities such as antimicrobial, anticancer, anti-inflammatory, and antiviral properties.

Upstream product

• 3900-89-8 2-Chlorobenzeneboronic acid 
• 615-43-0 2-iodophenylamine 
• 1203-43-6 2'-chloro-[1,1'-biphenyl]-2-amine 
• 14498-97-6 2-chloro-2'-iodobiphenyl 
• 3209-22-1 1,2-Dichloro-3-nitrobenzene 
• 98-80-6 phenylboronic acid 
• 140665-55-0 2-chloro-6-nitro-1,1'-biphenyl 
• 2312-23-4 m-chlorophenylhydrazine hydrochloride 
• 108-94-1 cyclohexanone 
• 1140969-80-7 C₁₂H₈ClN₃ 
• 873416-60-5 9-acetyl-5-chloro-1,2,3,4-tetrahydro-carbazole 
• 262606-98-4 2-[(3-chloro-phenyl)-phenyl-amino]-isoindole-1,3-dione 
• 56-23-5 tetrachloromethane 
• 86-74-8 9H-carbazole 

Downstream Products

• 1431879-05-8 4-chloro-6-phenyl-9-(4-biphenylyl)carbazole 
• 1431878-98-6 4-chloro-9-(4-biphenylyl)carbazole 
• 1431879-01-4 4-chloro-9-[4-(2-pyridyl)phenyl]carbazole 

Relevant articles and documents

Nitrogen-Iodine Exchange of Diaryliodonium Salts: Access to Acridine and Carbazole

A nitrogen-iodine exchange protocol of diaryliodonium salts with sodium azide salt is developed for general construction of significant functional acridines and carbazoles, in which introduction of nitrogen at a late stage was successfully established avoiding heteroatom incompatibility. Inorganic sodium azide served as the sole nitrogen atom source in this transformation. The diversiform functional acridines and carbazoles were comprehensively achieved through annulated diaryliodonium salts, respectively. Notably, Acridine orange (a fluorescent indicator for cell lysosomal dye) and Carprofen (a nonsteroidal anti-inflammatory drug) were efficiently established through this protocol.

4 - nitrocarbazoles compound and use thereof

PROBLEM TO BE SOLVED: To provide a compound for an organic EL element which has high luminous efficiency and excellent durability.SOLUTION: A 4-aminocarbazole compound is represented by general formula (1) [where Arto Areach independently represent a C6-C20 aromatic hydrocarbon group, a C3-C20 heteroaromatic group containing at least one oxygen, nitrogen, or sulfur atom, or the like; Arrepresents a C6-C17 aromatic hydrocarbon group or the like; X represents a C6-C20 divalent aromatic hydrocarbon group or the like; and Rto Reach independently represent a C6-C20 aromatic hydrocarbon group or the like].

Rh(I)-catalyzed decarbonylation synthesis of carbazoles via C-N cleavage

A one-pot Rh(I)-catalyzed synthesis of 9-H carbazoles via C-N bond cleavage by activation of aldehyde C-H bonds is reported. This protocol offers good yields and tolerates a broad range of functional groups. Based on the extensive control experiments, we propose a plausible decarbonylation mechanism.