365423-59-2

Basic information

• Product Name: 5-[(E)-3-(2-Bromo-1-ethoxy-ethoxy)-propenyl]-1,2,3-trimethoxy-benzene
• Synonyms: 5-[(E)-3-(2-Bromo-1-ethoxy-ethoxy)-propenyl]-1,2,3-trimethoxy-benzene
• CAS NO: 365423-59-2
• Molecular Weight: 375.26
• Mol File: 365423-59-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-[(E)-3-(2-Bromo-1-ethoxy-ethoxy)-propenyl]-1,2,3-trimethoxy-benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[(E)-3-(2-Bromo-1-ethoxy-ethoxy)-propenyl]-1,2,3-trimethoxy-benzene(365423-59-2)
• EPA Substance Registry System: 5-[(E)-3-(2-Bromo-1-ethoxy-ethoxy)-propenyl]-1,2,3-trimethoxy-benzene(365423-59-2)

Safety Data

• Hazardous Substances Data: 365423-59-2(Hazardous Substances Data)

Upstream product

• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 1878-29-1 ethyl (E)-3-(3,4,5-trimethoxyphenyl)acrylate 
• 1504-56-9 (E)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-ol 
• 109-92-2 ethyl vinyl ether 

Relevant articles and documents

Radical cyclisation based approach to lignans. Synthesis of 4-arylmethyldihydrofuran-2-ones

Bromoacetalisation of the cinnamyl alcohols 7a-d, obtained from the corresponding benzaldehydes, generated the bromoacetals 10a-d. The 5-exo trig radical cyclisation of the bromoacetals 10a-d followed by one step hydrolysis-oxidation of the resulting cyclic acetals 11a-d furnished the title compounds 6a-d, respectively, well-established intermediates of a variety of lignans.