365449-54-3

Basic information

• Product Name: (1S,2R)-1-(tosylamino)-2,3-dihydro-1H-inden-2-yl pent-4-enoate
• Synonyms: (1S,2R)-1-(tosylamino)-2,3-dihydro-1H-inden-2-yl pent-4-enoate
• CAS NO: 365449-54-3
• Molecular Weight: 385.484
• Mol File: 365449-54-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (1S,2R)-1-(tosylamino)-2,3-dihydro-1H-inden-2-yl pent-4-enoate(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,2R)-1-(tosylamino)-2,3-dihydro-1H-inden-2-yl pent-4-enoate(365449-54-3)
• EPA Substance Registry System: (1S,2R)-1-(tosylamino)-2,3-dihydro-1H-inden-2-yl pent-4-enoate(365449-54-3)

Safety Data

• Hazardous Substances Data: 365449-54-3(Hazardous Substances Data)

Upstream product

• 591-80-0 pent-4-enoic acid 
• 171562-32-6 N-((1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl)-4-methylbenzenesulfonamide 
• 98-59-9 p-toluenesulfonyl chloride 
• 7480-35-5 (1S,2R)-1-amino-2-indanol 

Downstream Products

• 540770-25-0 (2S,1'S)-2-(2'-benzyloxy-1'-hydroxyethyl)pent-4-enoic acid 
• 365449-55-4 (2S,1'S,1S,2R)-1-p-tosylaminoindan-2-yl 2-(2'-benzyloxy-1'-hydroxyethyl)pent-4-enoate 

Relevant articles and documents

A stereoselective anti-aldol route to (3R,3aS,6aR)-hexahydrofuro[2,3-b] furan-3-ol: A key ligand for a new generation of HIV protease inhibitors

A stereoselective synthesis of (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-ol, an important high affinity P2-ligand, in high enantiomeric excess (>99%) is reported. The synthesis features an ester-derived titanium enolate based highly stereoselective anti-aldol reaction as the key step. Georg Thieme Verlag Stuttgart.

Stereoselective synthesis of pseudopeptide microbial agent AI-77-B.

[structure: see text]. An efficient and highly stereoselective synthesis of the gastroprotective natural product AI-77-B is described. The stereocenters of the hydroxy amino acid moiety were generated by an ester-derived titanium-enolate-mediated syn-aldo