365513-09-3

Basic information

• Product Name: (3-tert-butoxycarbonylmethoxy-2-tert-butoxycarbonylmethoxymethyl-2-phenyl-propoxy)-acetic acid tert-butyl ester
• Synonyms: (3-tert-butoxycarbonylmethoxy-2-tert-butoxycarbonylmethoxymethyl-2-phenyl-propoxy)-acetic acid tert-butyl ester
• CAS NO: 365513-09-3
• Molecular Weight: 524.652
• Mol File: 365513-09-3.mol

Chemical Properties

• CAS DataBase Reference: (3-tert-butoxycarbonylmethoxy-2-tert-butoxycarbonylmethoxymethyl-2-phenyl-propoxy)-acetic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (3-tert-butoxycarbonylmethoxy-2-tert-butoxycarbonylmethoxymethyl-2-phenyl-propoxy)-acetic acid tert-butyl ester(365513-09-3)
• EPA Substance Registry System: (3-tert-butoxycarbonylmethoxy-2-tert-butoxycarbonylmethoxymethyl-2-phenyl-propoxy)-acetic acid tert-butyl ester(365513-09-3)

Safety Data

• Hazardous Substances Data: 365513-09-3(Hazardous Substances Data)

Upstream product

• 5292-43-3 bromoacetic acid tert-butyl ester 
• 4704-99-8 α,α,α-tris(hydroxymethyl)toluene 

Relevant articles and documents

New polypodal polycarboxylic ligands - Complexation of rare-earth ions in aqueous solution

The complexation ability of new polypodal carboxylic ligands prepared from 2,2-bis(hydroxymethyl)-1-alkanols was investigated in aqueous solution with Y3+ and various lanthanide ions (La3+, Sm3+, Eu3+, Gd3+, Tb3+, Dy3+). The values of the stability constants for ML complexes are of the order of 104 for the hexadentate trioxypropionates, 107 for the hexadentate trioxyacetates and 1014 for the nonadentate triaminohexaacetates. In these systems, the nitrogens of the amino groups seem to be better chelating atoms than the oxygens of the ether groups. The hydration numbers of dysprosium(III) complexes have been determined from the DyIII-induced 17O NMR water shifts.

Polyalkylation of 2,2-bis(hydroxymethyl)-1-alkanols with tert-butyl bromoacetate

A series of 2,2-bis(hydroxymethyl)-1-alkanols was poly-O-alkylated in satisfactory yields with the tert-butyl bromoacetate by phase transfer catalysis. The resulting pure polyesters were converted in polyacids in quantitative yields.