365517-26-6

Basic information

• Product Name: 2-amino-5,6,7,8-tetrahydro-7,7-dimethyl-4-(3-methylphenyl)-5-oxo-4H-chromene-3-carbonitrile
• Synonyms: 2-amino-5,6,7,8-tetrahydro-7,7-dimethyl-4-(3-methylphenyl)-5-oxo-4H-chromene-3-carbonitrile
• CAS NO: 365517-26-6
• Molecular Weight: 308.38
• Mol File: 365517-26-6.mol

Chemical Properties

• CAS DataBase Reference: 2-amino-5,6,7,8-tetrahydro-7,7-dimethyl-4-(3-methylphenyl)-5-oxo-4H-chromene-3-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-5,6,7,8-tetrahydro-7,7-dimethyl-4-(3-methylphenyl)-5-oxo-4H-chromene-3-carbonitrile(365517-26-6)
• EPA Substance Registry System: 2-amino-5,6,7,8-tetrahydro-7,7-dimethyl-4-(3-methylphenyl)-5-oxo-4H-chromene-3-carbonitrile(365517-26-6)

Safety Data

• Hazardous Substances Data: 365517-26-6(Hazardous Substances Data)

Upstream product

• 126-81-8 dimedone 
• 620-23-5 m-tolyl aldehyde 
• 109-77-3 malononitrile 

Relevant articles and documents

Ammonium acetate as a catalyst and/or reactant in the reaction of dimedone, aromatic aldehyde, and malononitrile: synthesis of tetrahydrobenzo[b]pyrans and hexahydroquinolines

Abstract: The reaction of aromatic aldehydes, dimedone, and malononitrile in the presence of ammonium acetate has afforded tetrahydrobenzo[b]pyrans instead of polyhydroquinolines under both grinding and reflux conditions; thus ammonium acetate acts as a c

Biguanide-functionalized hierarchical porous covalent organic frameworks for efficient catalysis of condensation reactions

Covalent organic frameworks (COFs) can be rationally designed with desired physicochemical properties for a far-ranging application in catalytic systems. Herein, a biguanide-functionalized covalent organic framework was designed and prepared via N-alkylat

Mechanical ball milling auxiliary synthesis method 2 -amino -3 - cyano - 4H - pyran compound

The invention relates to the technical field of chemical synthesis, and aims to solve the problems that 2 - amino -3 - cyano - 4H - pyran compounds are large in pollution and tedious in preparation in the prior art, and discloses a mechanical ball milling auxiliary synthesis method 2 -amino -3 - cyano - 4H - pyran compound which comprises the following steps: (a) the substrate 1. The substrate 2 and malononitrile were subjected to mechanical ball milling after addition of a protein catalyst and a grinding aid as a raw material. (b) Ball milling, the reactants are scraped off, the solvent is added, and the solvent is added, and after filtration, 2 - amino -3 - cyano - 4H - pyran compounds are prepared by column chromatography. The mechanical ball milling technology facilitates mutual contact of reactant molecules, realizes no solvent reaction, and is easily available to the environment. The method effectively realizes the green synthesis of 2 - amino -3 - cyano - 4H - pyran compounds, and is mild in preparation conditions, simple and convenient to operate and high in reaction rate.

Magnetized melamine-modified polyacrylonitrile (PAN@melamine/Fe3O4) organometallic nanomaterial: Preparation, characterization, and application as a multifunctional catalyst in the synthesis of bioactive dihydropyrano [2,3-c]pyrazole

An efficient magnetic polymer-based nanomaterial was prepared in three main steps including synthesis of polyacrylonitrile (PAN), modification of PAN with melamine, and magnetization of the PAN@melamine compound by in situ construction of Fe3O

Horsetail plant (Equisetum arvense) and horsetail plant ash: application and comparison of their catalytic activities as novel and natural porous lewis acid catalysts for the one-pot green synthesis of 2-amino-4H-chromene derivatives under solvent-free co

This study aims to use a new medicinal porous plant having a high content of silica known as horsetail and horsetail ash for the first time as novel, efficient, and environmentally friendly natural mild catalysts. The structure of these catalysts was char

MCM-41@Schiff base-Co(OAc)2 as an efficient catalyst for the synthesis of pyran derivatives

Heterogeneous ordered mesoporous silica materials catalyst, MCM-41@Schiff base-Co(AcO)2, reveals high catalytic performance within the synthesis of pyran derivatives using the multicomponent reaction of aldehydes, malononitrile and 2-naphthol (

Synthesis and characterization of a novel and green rod-like magnetic ZnS/CuFe2O4/agar organometallic hybrid catalyst for the synthesis of biologically-active 2-amino-tetrahydro-4H-chromene-3-carbonitrile derivatives

The magnetic biocompatible rod-like ZnS/CuFe2O4/agar organometallic hybrid catalyst was designed and prepared based on a natural macromolecule (agar) through a green and convenient method using inexpensive, nontoxic, and easily avail

Preparation and characterization of an eco-friendly ZnFe2O4@alginic acid nanocomposite catalyst and its application in the synthesis of 2-amino-3-cyano-4H-pyran derivatives

Alginic acid as a linear polysaccharide derived from natural resources can be used in the role of a green catalyst in organic reactions. Properties such as reactivity, renewability and biodegradability make this polysaccharide as an eco-friendly organocat

Efficient synthesis of 2-amino-3-cyano-4H-pyran derivatives via a non-catalytic one-pot three-component reaction

Abstract: A convenient one-pot multi-component strategy was conducted successfully under catalyst-free conditions employing water and PEG-400 as the efficient and cheap promoting medium. Three types and nearly 50 2-amino-3-cyano-4H-pyran annulated derivat

Sodium ethylene diamine tetraacetate catalyzed synthesis of chromene derivatives via multi-component reactions at low catalyst loading

An efficient and practical protocol for the synthesis of chromenes derivatives catalyzed by a low-loading sodium ethylene diamine tetraacetate (2?mol%) as a catalyst via multicomponent reaction is reported. A wide range of aromatic aldehydes easily underg