365553-89-5Relevant academic research and scientific papers
Structure-activity relationship of linear peptide Bu-His-DPhe-Arg-Trp-Gly-NH2 at the human melanocortin-1 and -4 receptors: Histidine substitution
Cheung, Adrian Wai-Hing,Danho, Waleed,Swistok, Joseph,Qi, Lida,Kurylko, Grazyna,Rowan, Karen,Yeon, Mitch,Franco, Lucia,Chu, Xin-Jie,Chen, Li,Yagaloff, Keith
, p. 133 - 137 (2003)
Systematic substitution of His6 residue using non-selective hMC4R pentapeptide agonist (Bu-His6-DPhe7-Arg8-Trp9-Gly 10-NH2) as the template led to the identification of Bu-Atcsu
Selective cyclic peptides with melanocortin-4 receptor (MC4-R) agonist activity
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, (2008/06/13)
Peptides cyclized via disulfide or lactam bridges having melanocortin-4 receptor (MC4-R) agonist activity useful for treatment of obesity.
Selective linear peptides with melanocortin-4 receptor (MC4-R) agonist activity
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, (2008/06/13)
Peptides of formulae I, II and III selectively activate melanocortin-4 (MC-4) receptor activity.
