365996-65-2

Basic information

• Product Name: 5,6-Dihydro-4H-pyrrolo[3,4-d]thiazole HydrobroMide
• Synonyms: 5,6-Dihydro-4H-pyrrolo[3,4-d]thiazole HydrobroMide;5,6-DIHYDRO-4H-PYRROLO[3,4-D]THIAZOLE HBR
• CAS NO: 365996-65-2
• Molecular Formula: C5H7BrN2S
• Molecular Weight: 207.09148
• Mol File: 365996-65-2.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5,6-Dihydro-4H-pyrrolo[3,4-d]thiazole HydrobroMide(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6-Dihydro-4H-pyrrolo[3,4-d]thiazole HydrobroMide(365996-65-2)
• EPA Substance Registry System: 5,6-Dihydro-4H-pyrrolo[3,4-d]thiazole HydrobroMide(365996-65-2)

Safety Data

• Hazardous Substances Data: 365996-65-2(Hazardous Substances Data)

Usage

Description

5,6-Dihydro-4H-pyrrolo[3,4-d]thiazole Hydrobromide is a chemical compound that belongs to the class of pyrrolothiazole derivatives. It is a hydrobromide salt of the 5,6-dihydro-4H-pyrrolo[3,4-d]thiazole compound. This chemical has potential applications in the pharmaceutical industry as a building block for the synthesis of various organic compounds. Its unique structure and functional groups make it a valuable intermediate in the development of new drugs, agrochemicals, and materials. Additionally, it has properties that may make it useful in chemical research and exploration of new synthetic routes for organic chemistry.

Uses

Used in Pharmaceutical Industry:
5,6-Dihydro-4H-pyrrolo[3,4-d]thiazole Hydrobromide is used as a building block for the synthesis of various organic compounds, particularly in the development of new drugs, agrochemicals, and materials. Its unique structure and functional groups make it a valuable intermediate in the pharmaceutical industry.
Used in Chemical Research:
5,6-Dihydro-4H-pyrrolo[3,4-d]thiazole Hydrobromide is used as a valuable intermediate in chemical research, where it can be employed to explore new synthetic routes for organic chemistry and contribute to the advancement of the field.

Upstream product

• 365996-64-1 5-(benzenesulfonyl)-4,6-dihydro-5H-pyrrolo[3,4-d]thiazole 

Downstream Products

• 365996-66-3 5-Methyl-4,6-dihydro-5H-pyrrolo[3,4-d]thiazole 

Relevant articles and documents

Design, synthesis, and SAR of cis-1,2-diaminocyclohexane derivatives as potent factor Xa inhibitors. Part II: Exploration of 6-6 fused rings as alternative S1 moieties

A series of cis-1,2-diaminocyclohexane derivatives possessing a 6-6 fused ring for the S1 moiety were synthesized as novel factor Xa (fXa) inhibitors. The synthesis, structure-activity relationship (SAR), and physicochemical properties are reported herein, together with the discovery of compound 45c, which has potent anti-fXa activity, good physicochemical properties and pharmacokinetic (PK) profiles, including a reduced negative food effect.

DIAMINE DERIVATIVES

A compound represented by formula (1):Q1-Q2-To-N(R1) -Q3-N(R2)-T1-Q4 [wherein R1 and R2 are hydrogen atoms or the like; Q1 is a saturated or unsaturated, 5- or 6- membered cyclic hydrocarbon group which may be substituted, or the like; Q2 is a single bond or the like; Q3 represents the following group: (wherein Q5 is an alkylene group having 1 to 8 carbon atoms, or the like); and T0 and T1 are carbonyl groups or the like], a salt thereof, a solvate thereof, or an N-oxide thereof. The compound is useful as an agent for preventing and/or treating cerebral infarction, cerebral embolism, myocardial infarction, angina pectoris, pulmonary infarction, pulmonary embolism, Buerger's disease, deep venous thrombosis, disseminated intravascular coagulation syndrome, thrombus formation after artificial valve or joint replacement, thrombus formation and reocclusion after angioplasty, systemic inflammatory response syndrome (SIRS), multiple organ dysfunction syndrome (MODS), thrombus formation during extracorporeal circulation, or blood clotting upon blood drawing.

ETHYLENEDIAMINE DERIVATIVES

The invention relates a compound represented by the formula (1):Q1-Q2-C(=O)-N(R1)-Q3-N(R2)-T1-Q4 wherein R1 and R2 represent H or the like; Q1 represents an aromatic ring, heterocyclic ring or the like; Q2 represents a single bond, aromatic ring, heterocyclic ring or the like; Q3 represents a group or the like, Q4 represents an aromatic ring, heterocyclic ring or the like; and T1 represents -CO- or -SO2-, and a medicine which comprises the compound and is useful for thrombosis and embolism.