36629-61-5

Basic information

• Product Name: 1H-Indole-3-carboxamide, N-(2-fluorophenyl)-2,3-dihydro-1-methyl-2-oxo-
• Synonyms: N-(2-fluorophenyl)-1-methyl-2-oxo-3-indolinecarboxamide
• CAS NO: 36629-61-5
• Molecular Formula: C₁₆H₁₃FN₂O₂
• Molecular Weight: 284.2850232
• Mol File: 36629-61-5.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-Indole-3-carboxamide, N-(2-fluorophenyl)-2,3-dihydro-1-methyl-2-oxo-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole-3-carboxamide, N-(2-fluorophenyl)-2,3-dihydro-1-methyl-2-oxo-(36629-61-5)
• EPA Substance Registry System: 1H-Indole-3-carboxamide, N-(2-fluorophenyl)-2,3-dihydro-1-methyl-2-oxo-(36629-61-5)

Safety Data

• Hazardous Substances Data: 36629-61-5(Hazardous Substances Data)

Upstream product

• 16744-98-2 1-Fluoro-2-isocyanato-benzene 
• 61-70-1 N-methyl-2-indolinone 

Relevant articles and documents

Enantioselective Arylation of 3-Carboxamide Oxindoles with Quinone Monoimines and Synthesis of Chiral Spirooxindole-benzofuranones

A highly enantioselective arylation of 3-carboxamide oxoindoles with quinone monoimines is described. Various 3-aryl-3-carboxamide oxindoles with an all-carbon quaternary center were obtained in moderate to good yields (up to 99%) with moderate to good enantioselectivities (up to 98%) in the presence of a bifunctional thiourea-tertiary amine catalyst. The absolute configuration of one product was determined by an X-ray crystal structural analysis and the absolute configurations of the other products can be assigned by analogy. Moreover, several chiral spirooxindole-benzofuranones were synthesized from the 3-aryl-3-carboxamide oxindoles in moderate yields with moderate to good enantioselectivities.