3663-23-8Relevant articles and documents
4-butylbenzene-1,2-diamine synthesis method
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Paragraph 0003; 0014-0016, (2018/11/03)
The invention discloses 4-butylbenzene-1,2-diamine synthesis method. The method includes steps: dissolving 4-butyl-2-nitroaniline into a solvent, adding aqueous solution which contains sodium sulfide,sodium thiosulfate and sodium hydrosulfite, performing heating reaction and TLC detection, filtering after reaction is finished, performing organic solvent extraction, and evaporating organic solventextract liquid to dry to obtain 4-butylbenzene-1,2-diamine. The method is low in equipment requirement, simple in operation, low in cost and suitable for industrial production, the reaction yield reaches 89.2%, and the crude product purity reaches 97% or above.
BENZIIMIDAZOLE AND IMIDAZOPYRIDINE DERIVATIVES AS SODIUM CHANNEL MODULATORS
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, (2013/08/15)
The invention relates to benzimidazole and imidazopyridine derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to new Nav1.8 modulators of formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, R7. X and Y are as defined in the description. Nav1.8 modulators are potentially useful in the treatment of a wide range of disorders, particularly pain.
Organo-metal compositions, preparation and use
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, (2008/06/13)
Complexes of a transition metal and a tetrasubstituted aromatic compound which contain at least two transition metal atoms. At least two of the substituents are -SH groups, the other two substituents being -SH, -OH and -NHR. The complexes are prepared by reacting the tetrasubstituted aromatic compound with a transition metal compound in the presence of a disubstituted aromatic compound. Depending on the relative proportions of the di- and tetra--substituted compounds, the resulting complex may contain more than one residue from the tetra-substituted compound and more than two transition metal atoms. The complexes possess infra-red absorbing properties which vary in dependence on the particular complex, the complexes with more than one residue from the tetrasubstituted compound absorbing radiation of longer wavelength. The compounds can be used to provide infra-red absorbing compositions, for example as a coating or inter-layer for glass. The complexes may be used together with one or more different infra-red absorbing materials. The tetra-substituted aromatic compound may be a tetra-thiol and this can be prepared from an aromatic compound containing at least four halogen substituents by reaction with an alkaline thiol compound in the presence of iron and sulphur in a polar solvent such as dimethyl formamide.