36639-87-9Relevant academic research and scientific papers
Structure-guided design of novel thiazolidine inhibitors of O -Acetyl serine sulfhydrylase from mycobacterium tuberculosis
Poyraz, ?mer,Jeankumar, Variam Ullas,Saxena, Shalini,Schnell, Robert,Haraldsson, Martin,Yogeeswari, Perumal,Sriram, Dharmarajan,Schneider, Gunter
supporting information, p. 6457 - 6466 (2013/09/23)
The cysteine biosynthetic pathway is absent in humans but essential in microbial pathogens, suggesting that it provides potential targets for the development of novel antibacterial compounds. CysK1 is a pyridoxalphosphate- dependent O-acetyl sulfhydrylase
3-amino-2-mercaptobenzoic acid derivatives and processes for their preparation
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, (2008/06/13)
Compounds of the formula I STR1 and disulfides thereof and salts thereof are important intermediate products for the preparation of compounds having a microbicidal and plant-immunizing action, of the formula III STR2 In the compounds of the formulae I and III: X is halogen, n is 0,1,2 or 3; Z is CN, CO-A or CS-A, A is hydrogen, halogen, OR1, SR2 and N(R3)R4 ; R1 to R 4 are hydrogen, a substituted or unsubstituted, open-chain, saturated or unsaturated hydrocarbon radical containing not more than 8 carbon atoms, a substituted or unsubstituted cyclic, saturated or unsaturated hydrocarbon radical containing not more than 10 carbon atoms, substituted or unsubstituted benzyl or phenethyl, a substituted or unsubstituted alkanoyl group containing not more than 8 carbon atoms, a substituted or unsubstituted benzoyl group or a substituted or unsubstituted heterocyclyl radical; or R3 and R4, together with the nitrogen atom to which they are bonded, are a 5- or 6-membered, substituted or unsubstituted heterocyclic radical having 1-3 heteroatoms O,S and/or N. Processes for the preparation of compounds of the formula I are described.
