3664-61-7Relevant academic research and scientific papers
On the mechanism of the intramolecular samarium barbier reaction. Probes for formation of radical and organosamarium intermediates
Curran, Dennis P.,Gu, Xin,Zhang, Wei,Dowd, Paul
, p. 9023 - 9042 (1997)
A new type of mechanistic probe for the intramolecular samarium Barbier reaction has been designed, and two different probe substrates have been investigated in detail. Remarkably, no unambiguous evidence could be obtained in favor of any of the obvious intermediates (free alkyl or alkoxy radicals, ketyls, organosamarium species) that are postulated for this reaction. Several possibilities for modified mechanisms are suggested.
Clemmensen Reduction. XI. Fragmentation Reactions of Some 3-Acetylcycloalkanones
Bailey, Karen E.,Davis, Brian R.
, p. 1827 - 1834 (2007/10/03)
Clemmensen reduction of a series of 3-acetylcycloalkanones yields, as the major product, an acyclic unsaturated ketone, the product of fragmentation.Some normal carbonyl-methylene reduction also occurs.A mechanistic rationale for the fragmentation is advanced.
