366452-06-4

Upstream product

• 714962-11-5 2'-benzyloxy-3'-bromo-5'-t-butyldimethylsilyloxyacetophenone 
• 843644-61-1 1-(2'-benzyloxy-3'-bromo-5'-t-butyldimethylsilyloxyphenyl)-ethanol 
• 714962-15-9 (α'R,2R)-2-(2'-benzyloxy-3'-bromo-5'-t-butyldimethylsilyloxy-α'-methylbenzyloxy)propanal 
• 714962-12-6 methyl (α'SR,2R)-2-(2'-benzyloxy-3'-bromo-5'-t-butyldimethylsilyloxy-α'-methylbenzyloxy)propanoate 
• 714962-13-7 (α'R,2R)-2-(2'-benzyloxy-3'-bromo-5'-t-butyldimethylsilyloxy-α'-methylbenzyloxy)propanol 
• 490-78-8 2,5-Dihydroxyacetophenone 
• 843644-62-2 2'-benzyloxy-3'-bromo-5'-t-butyldimethylsilyloxy-α'-methylbenzyl-2,2,2-trichloroethanimidate 
• 843644-60-0 3'-bromo-5'-t-butyldimethylsilyloxy-2'-hydroxyacetophenone 
• 843644-58-6 5'-t-butyldimethylsilyloxy-2'-hydroxyacetophenone 
• 366452-04-2 (α'R,2R)-2-(2'-benzyloxy-3'-bromo-5'-hydroxy-α'-methylbenzyloxy)propanal 

Downstream Products

• 366452-08-6 (1R,3R,4S)-8-benzyloxy-7-bromo-4-hydroxy-3,4-dihydro-1,3-dimethyl-5-methoxybenzo[c]pyran 
• 366452-09-7 (1R,3R,4R)-8-benzyloxy-7-bromo-3,4-dihydro-4-hydroxy-1,3-dimethyl-5-methoxybenzo[c]pyran 

Relevant academic research and scientific papers

Syntheses in enantiopure form of four diastereoisomeric naphthopyranquinones derived from aphid insect pigments

The first syntheses are described of the four enantiopure naphthopyranquinones (1R,3R,4S)- and (1R,3R,4R)-3,4-dihydro-4,7,9-trihydroxy-1, 3-dimethylnaphtho[2,3-c]pyranquinone (quinone A 1 and quinone A' 2) and their two C-3 epimers, the (1R,3S,4S)- and (1

The diastereoselective syntheses of enantiopure benzo- and naphtho-pyrans related to the aphid insect pigments

An overview is presented of synthetic endeavours directed towards the assembly of the enantiopure quinone A and quinone A′, natural derivatives of the aphid insect pigments protoaphin-fb and protoaphin-sl. These are achieved through intramolecular diaster

Asymmetric diastereoselective syntheses of the aphid insect pigment derivatives quinone A and quinone A′

Commercially available (R)-lactate has been used to provide the chiral source for the asymmetric diastereoselective syntheses of all four stereoisomers of 3,4-dihydro-4,7,9-trihydroxy-1,3-dimethylnaphtho[2,3-c]pyran-5,10-quinone based on 3R stereochemistr