366477-70-5

Basic information

• Product Name: 1-(2,2-dimethyl-[1,3]dioxolan-4-yl)-3-p-tolyl-prop-2-yn-1-ol
• CAS NO: 366477-70-5
• Molecular Weight: 246.306
• Mol File: 366477-70-5.mol

Chemical Properties

• CAS DataBase Reference: 1-(2,2-dimethyl-[1,3]dioxolan-4-yl)-3-p-tolyl-prop-2-yn-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,2-dimethyl-[1,3]dioxolan-4-yl)-3-p-tolyl-prop-2-yn-1-ol(366477-70-5)
• EPA Substance Registry System: 1-(2,2-dimethyl-[1,3]dioxolan-4-yl)-3-p-tolyl-prop-2-yn-1-ol(366477-70-5)

Safety Data

• Hazardous Substances Data: 366477-70-5(Hazardous Substances Data)

Upstream product

• 22323-80-4 (4S)-2,2-dimethyl-[1,3]dioxolane-4-carbaldehyde 
• 766-97-2 4-n-methylphenylacetylene 

Relevant articles and documents

Synthesis and intramolecular cyclization of diethylphosphono-substituted allenic glycols

This paper describes a convenient and efficient synthesis of new (2R)-5-substituted-5-(diethylphosphono)-penta-3,4-dien-1,2-diols. Phosphorylated allenic glycols are stable enough compounds, but under basic conditions they cyclized to (3R)-5-(3-hydroxy-2,3-dihydrofuryl) (diethylphosphono)alkanes through intramolecular nucleophilic addition of the terminal alkoxide to the central carbon atom of the allene system. Treatment of (3R)-5-(3hydroxy-2,3-dihydrofuryl)(diethylphosphono)alkanes with a catalytic amount of p-toluenesulfonic acid in chloroform at 40-45 °C for 0.5 hours afforded diethylphosphono(2-furyl)alkanes.