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366783-29-1

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366783-29-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 366783-29-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,6,6,7,8 and 3 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 366783-29:
(8*3)+(7*6)+(6*6)+(5*7)+(4*8)+(3*3)+(2*2)+(1*9)=191
191 % 10 = 1
So 366783-29-1 is a valid CAS Registry Number.

366783-29-1Downstream Products

366783-29-1Relevant articles and documents

A lysosome-targeted near-infrared photosensitizer for photodynamic therapy and two-photon fluorescence imaging

Tu, Yinuo,Wang, Lei,Wu, Xu,Xia, Weikang

, p. 6098 - 6107 (2021/07/21)

Organelle-targeted two-photon near-infrared photosensitizers are highly desirable for photodynamic therapy (PDT) of cancer. Herein, in this contribution, we have developed a 2-dicyanomethylenethiazole-based D-π-A structured near-infrared photosensitizer (TTR).TTRexhibits near-infrared emission (704 nm), a large Stokes shift (200 nm), and smaller ΔES1-T1(the energy gap between S1and T1) (0.717 eV).In vitroresults show thatTTRcan specifically target lysosomes in living cells for near-infrared fluorescence imaging. With efficient ROS generation, excellent biocompatibility, two-photon imaging capability, and depth imaging (21 μmin vitroand 210 μmin vivo),TTRcan effectively kill tumor cells and inhibit the growth of subcutaneous tumors. The hematoxylin-eosin (H&E) staining and blood biochemical parameter results further prove the biocompatibility ofTTR. Hence,TTRcan be a promising photosensitizer for PDT.

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