366808-12-0

Basic information

• Product Name: (Z)-2-hydroxystyryl-2,4,6-trimethoxybenzylsulfone
• Synonyms: (Z)-2-hydroxystyryl-2,4,6-trimethoxybenzylsulfone
• CAS NO: 366808-12-0
• Molecular Weight: 364.419
• Mol File: 366808-12-0.mol

Chemical Properties

• CAS DataBase Reference: (Z)-2-hydroxystyryl-2,4,6-trimethoxybenzylsulfone(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-2-hydroxystyryl-2,4,6-trimethoxybenzylsulfone(366808-12-0)
• EPA Substance Registry System: (Z)-2-hydroxystyryl-2,4,6-trimethoxybenzylsulfone(366808-12-0)

Safety Data

• Hazardous Substances Data: 366808-12-0(Hazardous Substances Data)

Upstream product

• 5101-44-0 2-ethynyl-phenol 
• 212555-23-2 (2,4,6-trimethoxyphenyl)methanethiol 

Relevant articles and documents

Substituted styryl benzylsulfones for treating proliferative disorders

Styryl benzylsulfones of formula I are useful as antiproliferative agents, including, for example, anticancer agents: wherein (a) (i) at least three of R1, R2, R3, R4 and R5 are independently selected from the group consisting of halogen, C1-C6 alkyl, C1-C6 alkoxy, nitro, cyano, carboxyl, hydroxyl, phosphonato, amino, sulfamyl, acetoxy, dimethylamino(C2-C6 alkoxy) and trifluoromethyl, and the balance of said R1, R2, R3, R4 and R5 are independently selected from the group consisting of hydrogen, halogen, C1-C6 alkyl, C1-C6 alkoxy, nitro, cyano, carboxyl, hydroxyl, phosphonato, amino, sulfamyl, acetoxy, dimethylamino(C2-C6 alkoxy) and trifluoromethyl; and (ii) R6, R7, R8, R9 and R10 are independently selected from the group consisting of hydrogen, halogen, C1-C6 alkyl, C1-C6 alkoxy, nitro, cyano, carboxyl, hydroxyl, phosphonato, amino, sulfamyl, acetoxy, dimethylamino(C2-C6 alkoxy) and trifluoromethyl; or (b) (i) at least three of R6, R7, R8, R9 and R10 are independently selected from the group consisting of halogen, C1-C6 alkyl, C1-C6 alkoxy, nitro, cyano, carboxyl, hydroxyl, phosphonato, amino, sulfamyl, acetoxy, dimethylamino(C2-C6 alkoxy) and trifluoromethyl, and the balance of said R6, R7, R8, R9 and R10 are independently selected from the group consisting of hydrogen, halogen, C1-C6 alkyl, C1-C6 alkoxy, nitro, cyano, carboxyl, hydroxyl, phosphonato, amino, sulfamyl, acetoxy, dimethylamino(C2-C6 alkoxy) and trifluoromethyl; and (ii) R1, R2, R3, R4 and R5 are independently selected from the group consisting of hydrogen, halogen, C1-C6 alkyl, C1-C6 alkoxy, nitro, cyano, carboxyl, hydroxyl, phosphonato, amino, sulfamyl, acetoxy, dimethylamino(C2-C6 alkoxy) and trifluoromethyl; or a pharmaceutically acceptable salt thereof.