36681-40-0Relevant academic research and scientific papers
Hydroperoxidations of Alkenes using Cobalt Picolinate Catalysts
Peralta-Neel, Zulema,Woerpel
, p. 5002 - 5006 (2021)
Hydroperoxides were synthesized in one step from various alkenes using Co(pic)2as the catalyst with molecular oxygen and tetramethyldisiloxane (TMDSO). The hydration product could be obtained using a modified catalyst, Co(3-mepic)2, with molecular oxygen and phenylsilane. Formation of hydroperoxides occurred through a rapid Co-O bond metathesis of a peroxycobalt compound with isopropanol.
Extractive biocatalysis in the asymmetric reduction of α-alkyl, β-aryl enones by Baker's yeast
Silva, Rafaela M.,Okano, Laura T.,Rodrigues, J. Augusto R.,Clososki, Giuliano C.
, p. 939 - 944 (2017/07/11)
We prepared various chiral α-alkyl, β-aryl ketones with good to excellent enantiomeric excess through the Baker's yeast asymmetric double-bond reduction of the corresponding α,β-unsaturated substrates adsorbed onto the resin Amberlite XAD-7. This methodology was compatible with substrates bearing both electron-donating and withdrawing groups attached to the aromatic ring. Elongation of the α-alkyl substituent of the starting material strongly affected the reactivity and enantioselectivity of the reaction.
