36725-21-0

Downstream Products

• 52240-10-5 4-(1,6-dihydro-6-oxo-3-pyridazinyl)benzonitrile 
• 109764-50-3 6-[4-(1H-imidazol-2-yl)phenyl]-3(2H)-pyridazinone 
• 109890-17-7 6-<4-(4,5-dihydro-1H-imidazol-2-yl)phenyl>-4,5-dihydro-3(2H)-pyridazinone 
• 109890-15-5 4,5-dihydro-6-[4-(1H-tetrazol-5-yl)phenyl]-3(2H)-pyridazinone 
• 109890-16-6 4-(1,4,5,6-tetrahydro-6-oxo-3-pyridazinyl)benzenecarbothioamide 

Relevant academic research and scientific papers

Substituted 6-phenyl-3(2H)-pyridazinones useful as cardiotonic agents

Substituted 6-phenyl-3(2H)-pyridazinone compounds are useful as cardiotonic agents. Said compounds cause a significant increase in myocardial contractility in the anesthetized dog. Said compounds are produced by reacting substituted γ-oxobenzenebutanoic acids with suitably substituted hydrazines to provide 6-phenyl-4,5-dihydro-3(2H)-pyridazinones which are dehydrogenated to the desired product. The intermediate 6-phenyl-4,5-dihydro-3(2H)-pyridazinones are themselves useful as cardiotonic agents.