Cas 367260-08-0,(7R,9S,12S)-6-Benzenesulfonyl-12-cyclohexyl-11,14-dioxo-2-oxa-6,10,13-triaza-tricyclo[14.3.1.1<sup>7,10</sup>]henicosa-1<sup>(20)</sup>,16,18-triene-9-carboxylic acid

367260-08-0

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Basic information

Product Name: (7R,9S,12S)-6-Benzenesulfonyl-12-cyclohexyl-11,14-dioxo-2-oxa-6,10,13-triaza-tricyclo[14.3.1.1^7,10]henicosa-1⁽²⁰⁾,16,18-triene-9-carboxylic acid
Synonyms: (7R,9S,12S)-6-Benzenesulfonyl-12-cyclohexyl-11,14-dioxo-2-oxa-6,10,13-triaza-tricyclo[14.3.1.1^7,10]henicosa-1⁽²⁰⁾,16,18-triene-9-carboxylic acid
CAS NO:367260-08-0
Molecular Formula:
Molecular Weight: 583.706
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: (7R,9S,12S)-6-Benzenesulfonyl-12-cyclohexyl-11,14-dioxo-2-oxa-6,10,13-triaza-tricyclo[14.3.1.1^7,10]henicosa-1⁽²⁰⁾,16,18-triene-9-carboxylic acid(CAS DataBase Reference)
NIST Chemistry Reference: (7R,9S,12S)-6-Benzenesulfonyl-12-cyclohexyl-11,14-dioxo-2-oxa-6,10,13-triaza-tricyclo[14.3.1.1^7,10]henicosa-1⁽²⁰⁾,16,18-triene-9-carboxylic acid(367260-08-0)
EPA Substance Registry System: (7R,9S,12S)-6-Benzenesulfonyl-12-cyclohexyl-11,14-dioxo-2-oxa-6,10,13-triaza-tricyclo[14.3.1.1^7,10]henicosa-1⁽²⁰⁾,16,18-triene-9-carboxylic acid(367260-08-0)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 367260-08-0(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 367260-08-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,6,7,2,6 and 0 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 367260-08:
(8*3)+(7*6)+(6*7)+(5*2)+(4*6)+(3*0)+(2*0)+(1*8)=150
150 % 10 = 0
So 367260-08-0 is a valid CAS Registry Number.

367260-08-0Upstream product

367259-21-0 methyl (7R,9S,12S)-12-cyclohexyl-11,14-dioxo-6-(phenylsulfonyl)-2-oxa-6,10,13-triazatricyclo[14.3.1.1^7,10]heneicosa-1⁽²⁰⁾,16,18-triene-9-carboxylate

367260-08-0Downstream Products

368871-41-4 (7R,9S,12S)-6-Benzenesulfonyl-12-cyclohexyl-11,14-dioxo-2-oxa-6,10,13-triaza-tricyclo[14.3.1.1^7,10]henicosa-1⁽²⁰⁾,16,18-triene-9-carboxylic acid {1-[({[((S)-dimethylcarbamoyl-phenyl-methyl)-carbamoyl]-methyl}-carbamoyl)-hydroxy-methyl]-butyl}-amide

367260-08-0Relevant academic research and scientific papers

Novel potent hepatitis C virus NS3 serine protease inhibitors derived from proline-based macrocycles

Chen, Kevin X.,Njoroge, F. George,Arasappan, Ashok,Venkatraman, Srikanth,Vibulbhan, Bancha,Yang, Weiying,Parekh, Tejal N.,Pichardo, John,Prongay, Andrew,Cheng, Kuo-Chi,Butkiewicz, Nancy,Yao, Nanhua,Madison, Vincent,Girijavallabhan, Viyyoor

, p. 995 - 1005 (2007/10/03)

The hepatitis C virus (HCV) NS3 protease is essential for viral replication. It has been a target of choice for intensive drug discovery research. On the basis of an active pentapeptide inhibitor, 1, we envisioned that macrocyclization from the P2 proline

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