367281-07-0

Basic information

• Product Name: toluene-4-sulfonic acid 3,7-bis(2-fluorophenyl)-4-methylpyrazolo[1,5-d][1,2,4]triazin-2-yl ester
• CAS NO: 367281-07-0
• Molecular Weight: 492.506
• Mol File: 367281-07-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: toluene-4-sulfonic acid 3,7-bis(2-fluorophenyl)-4-methylpyrazolo[1,5-d][1,2,4]triazin-2-yl ester(CAS DataBase Reference)
• NIST Chemistry Reference: toluene-4-sulfonic acid 3,7-bis(2-fluorophenyl)-4-methylpyrazolo[1,5-d][1,2,4]triazin-2-yl ester(367281-07-0)
• EPA Substance Registry System: toluene-4-sulfonic acid 3,7-bis(2-fluorophenyl)-4-methylpyrazolo[1,5-d][1,2,4]triazin-2-yl ester(367281-07-0)

Safety Data

• Hazardous Substances Data: 367281-07-0(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 367281-05-8 toluene-4-sulfonic acid 4-(2-fluorophenyl)-5-(l-hydroxyethyl)-1H-pyrazol-3-yl ester 
• 367281-04-7 3-(2-fluorophenyl)-4-hydroxy-5-methyl-5H-furan-2-one 
• 367281-06-9 toluene-4-sulfonic acid 5-acetyl-4-(2-fluorophenyl)-1H-pyrazol-3-yl ester 
• 446-24-2 2-fluorobezohydrazide 

Downstream Products

• 367281-03-6 3,7-bis(2-fluorophenyl)-4-methyl-2-(2-methyl-2H-[1,2,4]triazol-3-ylmethoxy)pyrazolo[1,5-d][1,2,4]triazine 

Relevant articles and documents

Pyrazolo-triazine derivatives as ligands for gaba receptors

A class of substituted pyrazolo[1,5-d][1,2,4]triazine derivatives, possessing an optionally substituted cycloalkyl, phenyl or heteroaryl substituent at the 7-position, an alkyl group at the 4-position, and a substituted alkoxy moiety at the 2-position, are selective ligands for GABAA receptors, in particular having high affinity for the α2 and/or α3 subunit thereof, and are accordingly of benefit in the treatment and/or prevention of disorders of the central nervous system, including anxiety and convulsions.