367281-18-3

Upstream product

• 215868-81-8 (2-ethyl-2H-[1,2,4]triazol-3-yl)methanol 
• 367281-23-0 toluene-4-sulfonic acid 3-tert-butyl-7-(2,5-difluorophenyl)-4-methylpyrazolo[1,5-d][1,2,4]triazin-2-yl ester 
• 367281-20-7 4-tert-Butyl-5-(1-hydroxyethyl)-3-(4-methyl-phenyl)sulfonyloxypyrazole 
• 265644-03-9 2,5-difluorobenzohydrazide 
• 367281-22-9 5-Acetyl-4-tert-butyl-3-(4-methylphenyl)sulfonyloxypyrazole 

Relevant academic research and scientific papers

Pyrazolo-triazine derivatives as ligands for gaba receptors

A class of substituted pyrazolo[1,5-d][1,2,4]triazine derivatives, possessing an optionally substituted cycloalkyl, phenyl or heteroaryl substituent at the 7-position, an alkyl group at the 4-position, and a substituted alkoxy moiety at the 2-position, are selective ligands for GABAA receptors, in particular having high affinity for the α2 and/or α3 subunit thereof, and are accordingly of benefit in the treatment and/or prevention of disorders of the central nervous system, including anxiety and convulsions.