367491-79-0

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 688036-02-4 5-O-[(tert-butyl)diphenylsilyl]-2,3-dideoxy-2-fluoro-3-[hydroxy(methyl)amino]-D-arabino-1,4-lactone 

Downstream Products

• 367491-83-6 1-{5'-O-[(tert-butyl)diphenylsilyl]-2',3'-dideoxy-2'-fluoro-3'-(hydroxyamino)-β-D-arabinofuranosyl}uracil 
• 367491-82-5 1-{5'-O-[(tert-butyl)diphenylsilyl]-2',3'-dideoxy-2'-fluoro-3'-[hydroxy(methyl)amino]-β-D-arabinofuranosyl}uracil 
• 367491-85-8 1-{5'-O-[(tert-butyl)diphenylsilyl]-2',3'-dideoxy-2'-fluoro-3'-[hydroxy(2-methylpropyl)amino]-β-D-arabinofuranosyl}uracil 
• 367491-84-7 1-{5'-O-[(tert-butyl)diphenylsilyl]-3'-[butyl(hydroxy)amino]-2',3'-dideoxy-2'-fluoro-β-D-arabinofuranosyl}uracil 
• 367491-81-4 1-{5'-O-[(tert-butyl)diphenylsilyl]-3'-({[(tert-butyl)dimethylsilyl]oxy}(methyl)amino)-2',3'-dideoxy-2'-fluoro-α-D-arabinofuranosyl}uracil 
• 367491-80-3 1-{5'-O-[(tert-butyl)diphenylsilyl]-3'-({[(tert-butyl)dimethylsilyl]oxy}(methyl)amino)-2',3'-dideoxy-2'-fluoro-β-D-arabinofuranosyl}uracil 
• 367491-86-9 1-{5'-O-[(tert-butyl)diphenylsilyl]-3'-[(cyclohexylmethyl)(hydroxy)amino]-2',3'-dideoxy-2'-fluoro-β-D-arabinofuranosyl}uracil 

Relevant academic research and scientific papers

Synthesis of Potentially Antiviral 2′,3′-Dideoxy-2′ -fluoro-3′-(hydroxyamino)nucleosides

A series of novel 3′-(alkyl(hydroxy)amino)-2′-fluoronucleoside analogs were prepared via conjugate addition of N-methylhydroxylamine to various 2-fluorobutenolides. The adducts 13a and 16 were obtained as single isomers under absolute control of stereoche