36752-47-3

Upstream product

• 2389-45-9 Boc-Lys(Z)-OH 
• 7517-19-3 methyl (L)-leucinate hydrochloride 
• 34404-36-9 Boc-Lys(Z)-OSu 
• 23082-32-8 Boc-Lys(εZ)-Leu-OMe 
• 82882-89-1 Z(OMe)-Lys(Z)-Leu-OMe 

Downstream Products

• 90709-70-9 Z(OMe)-Arg(Mts)-Lys(Z)-Leu-OMe 
• 1381948-30-6 cyclo(L-Leu-Nε-Z-L-Lys) 
• 90709-74-3 Z(OMe)-Ala-Arg(Mts)-Lys(Z)-Leu-NHNH₂ 
• 90709-73-2 Z(OMe)-Ala-Arg(Mts)-Lys(Z)-Leu-OMe 
• 189131-86-0 (S)-2-((S)-2-{(S)-3-Benzyloxy-2-[11-(benzyloxycarbonyl-methyl-amino)-undecanoylamino]-propionylamino}-6-benzyloxycarbonylamino-hexanoylamino)-4-methyl-pentanoic acid methyl ester 
• 1026642-54-5 (S)-2-{(S)-2-[(S)-3-Benzyloxy-2-(11-tert-butoxycarbonylamino-undecanoylamino)-propionylamino]-6-benzyloxycarbonylamino-hexanoylamino}-4-methyl-pentanoic acid methyl ester 
• 1027153-54-3 (S)-2-{(S)-2-[(S)-2-(12-Azido-dodecanoylamino)-3-benzyloxy-propionylamino]-6-benzyloxycarbonylamino-hexanoylamino}-4-methyl-pentanoic acid methyl ester 
• 1027567-66-3 (S)-2-{(S)-2-[(S)-2-(10-Azido-decanoylamino)-3-benzyloxy-propionylamino]-6-benzyloxycarbonylamino-hexanoylamino}-4-methyl-pentanoic acid methyl ester 
• 1027163-02-5 (S)-2-{(S)-2-[(S)-2-(7-Azido-heptanoylamino)-3-benzyloxy-propionylamino]-6-benzyloxycarbonylamino-hexanoylamino}-4-methyl-pentanoic acid methyl ester 
• 189132-07-8 (S)-2-[(S)-2-((S)-3-Benzyloxy-2-tert-butoxycarbonylamino-propionylamino)-6-benzyloxycarbonylamino-hexanoylamino]-4-methyl-pentanoic acid methyl ester 

Relevant academic research and scientific papers

Cyclic dipeptides exhibit potency for scavenging radicals

Twenty kinds of cyclic dipeptides containing l-leucine were synthesized, and their antioxidant activity against .OH and O2·- was investigated. Compounds possessing polar amino acid residues, such as Asp, Cys, Glu, Lys, Pro, Ser, and Trp, exhibited higher antioxidant activity against .OH than vitamin E. However, only cyclo(l-Cys-l-Leu) scavenged O2·-.

Conformationally constrained [p-(ω-aminoalkyl)phenacetyl]-L-seryl-L- lysyl dipeptide amides as potent peptidomimetic inhibitors of Candida albicans and human myristoyl-CoA:protein N-myristoyl transferase

MyristoylCoA:protein N-myristoyltransferase (NMT) covalently attaches the 14-carbon saturated fatty acid myristate, via an amide bond, to the N- terminal glycine residues of a variety of cellular proteins. Genetic studies have shown that NMT is essential