36766-56-0Relevant academic research and scientific papers
Synthesis of Indolizines from Pyridinium Salts and Ethyl Bromodifluoroacetate
Hou, Xiaoya,Zhou, Sen,Li, Yuli,Guo, Minjie,Zhao, Wentao,Tang, Xiangyang,Wang, Guangwei
supporting information, p. 9313 - 9318 (2020/11/30)
Here we present a novel annulation of pyridinium salts with BrCF2CO2Et to access the indolizine derivatives with high efficiency. The α substitution of pyridine plays a key role in determining the reaction pathways. Various types of indolizines can be conveniently accessed from easily available pyridinium salts under mild and simple reaction conditions.
