36767-45-0

Basic information

• Product Name: 1,3-Diethyl-1,5,6,7-tetrahydroindazol-4-one
• Synonyms: 1,3-Diethyl-1,5,6,7-tetrahydroindazol-4-one;1,5,6,7-tetrahydro-1,3-dimethyl-4H-Indazol-4-one
• CAS NO: 36767-45-0
• Molecular Formula: C9H12N2O
• Molecular Weight: 164.20438
• Mol File: 36767-45-0.mol

Chemical Properties

• Boiling Point: 312.568°C at 760 mmHg
• Flash Point: 142.836°C
• Appearance: /
• Density: 1.25g/cm³
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.624
• CAS DataBase Reference: 1,3-Diethyl-1,5,6,7-tetrahydroindazol-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Diethyl-1,5,6,7-tetrahydroindazol-4-one(36767-45-0)
• EPA Substance Registry System: 1,3-Diethyl-1,5,6,7-tetrahydroindazol-4-one(36767-45-0)

Safety Data

• Hazardous Substances Data: 36767-45-0(Hazardous Substances Data)

Usage

Synonym

TEI-7286

Chemical Family

Indazole

Type

Tetrahydro derivative of indazol-4-one

Potential Applications

Pharmaceutical and research

Target Disorders

Neurological and psychiatric disorders (e.g., depression, anxiety)

Additional Potential

Treatment for opioid addiction and dependence

Significance

Valuable target for further research and development in medicinal chemistry

Chemical Structure

Features two ethyl groups at the 1,3-positions and a tetrahydro ring system

Molecular Weight

Approximately 204.27 g/mol (calculated from the molecular formula)

Appearance

Likely a solid, based on its molecular weight and structure

Stability

Stability information is not provided, but it may be influenced by factors such as temperature, light exposure, and the presence of air or moisture

Synthesis

The synthesis method is not provided, but it likely involves the formation of the indazol-4-one core and subsequent reduction and alkylation steps to introduce the tetrahydro and diethyl substituents.

InChI:InChI=1/C9H12N2O/c1-6-9-7(11(2)10-6)4-3-5-8(9)12/h3-5H2,1-2H3

Upstream product

• 60-34-4 methylhydrazine 
• 4056-73-9 2-acetyl-1,3-cyclohexanedione 

Relevant articles and documents

4,5,6,7-tetrahydroindazole derivatives as antitumor agents

Compounds which are 4,5,6,7-tetrahydroindazole derivative formula (1), wherein the dotted line (x) represents a single or double bond; n is 0 or 1; R1, R2 and R3 have the meanings reported in the description; Ra, R′a, Rb, R′b, Rc, R′c have the meanings reported in the description, also comprising that Ra and Rb together and/or Ra and Rc together form a N-alkylpiperydinyl ring with 1 to 6 carbon atoms in the alkyl chain or a phenyl ring; or pharmaceutically acceptable salts thereof, are useful for treating cell proliferative disorders and Alzheimer's disease.

SYNTHESIS OF ANGULAR BENZODIPYRAZOLES AND RELATED SYSTEMS

A series of benzodipyrazoles was prepared from cyclohexane-1,3-dione.Several related systems with different central rings were also prepared.In addition, benzodipyrazoles were synthesized from 1,4-cyclohexanedione monoethylene

Dipyrazoles and their use as bronchodilators

A group of variously methyl-substituted[1,2-c:3,4-c']dipyrazoles, cyclohepta[1,2-c:3,4-c']dipyrazoles, and cyclopenta[1,2-c:3,4-c']dipyrazoles useful as bronchodilators are described herein. The compounds are prepared by reacting a 1,3-diketone with hydra

Cycloalkane[1,2-c:4,3-c']dipyrazoles and their use as bronchodilators

The present invention is directed to a group of methylated tetrahydro cyclohepta[1,2-c:4,3-c']dipyrazoles and benzo[1,2-c:4,3-c']dipyrazoles useful as bronchodilators. The compounds are prepared by the reaction of an appropriate hydrazine with an appropri