3678-73-7Relevant articles and documents
Superacid-catalyzed reactions of pyridinecarboxaldehydes
Klumpp, Douglas A.,Zhang, Yiliang,Kindelin, Patrick J.,Lau, Siufu
, p. 5915 - 5921 (2006)
A variety of pyridinecarboxaldehydes are shown to give condensation products in high yields (80-99%, 10 examples) by reacting with benzene and CF3SO3H (triflic acid). In the superacidic solution, pyridinecarboxaldehydes can react with deactivated arenes (o-dichlorobenzene and nitrobenzene) and with saturated hydrocarbons (methylcyclohexane and adamantane). Dicationic intermediates from pyridinecarboxaldehydes in superacid (FSO3H-SbF5) have been directly observed using low temperature 13C NMR spectroscopy. Diprotonated pyridinecarboxaldehydes have also been studies using ab initio computational methods.
