367911-52-2Relevant academic research and scientific papers
Stereochemical considerations on the stereoselective cyclopropanation reactions of 3-aryl-2-phosphonoacrylates induced by the (-)-8-phenylmenthyl group as a chiral auxiliary
Takagi, Ryukichi,Hashizume, Miki,Nakamura, Minoru,Begum, Shahnaz,Hiraga, Yoshikazu,Kojima, Satoshi,Ohkata, Katsu
, p. 179 - 190 (2007/10/03)
The cyclopropanation of (-)-8-phenylmenthyl (E)-3-aryl-2-phosphonoacrylates E-3a-d with dimethyloxosulfonium methylide and diazomethane affords the corresponding trans cyclopropane derivatives as the major diastereomers with high diastereoselectivity. On
Stereoselective cyclopropanation of 3-aryl-2-phosphonoacrylates induced by the (-)-8-phenylmenthyl group as a chiral auxiliary
Takagi, Ryukichi,Nakamura, Minoru,Hashizume, Miki,Kojima, Satoshi,Ohkata, Katsuo
, p. 5891 - 5895 (2007/10/03)
The cyclopropanation of (-)-8-phenylmenthyl (E)-3-aryl-2-phosphonoacrylates with dimethyloxosulfonium methylide and diazomethane afforded the corresponding trans cyclopropane derivatives with high diastereoselectivity as the major diastereomer. The high selectivity is understandable in terms of the π-π interaction between the phenyl ring of the chiral auxiliary and the acrylate moiety.
