367967-44-0

Upstream product

• 83191-44-0 {4-methyl-2-[(2E)-1-methylbut-2-en-1-yl]phenyl}-amine 

Downstream Products

• 371192-50-6 Pentanoic acid [4-methyl-2-((E)-1-methyl-but-1-enyl)-phenyl]-amide 
• 371192-49-3 N-[4-methyl-2-(1-methyl-but-1-enyl)-phenyl]-acetamide 

Relevant academic research and scientific papers

Amidines: Synthesis from o-alkenylanilines and cyclization in polyphosphoric acid

Condensation of 2-[(E)-pent-3-en-2-yl]-4-, 2-[(E)-pent-2-en-2-yl]-4-, or 2-(cyclopent-1-enyl)-6-methylaniline with 1-chloro-1-(N-methylimino)-or 1-chloro-1-(N-phenylimino)ethane affords the corresponding amidines. Cyclization of the N-methylimino derivatives in polyphosphoric acid gives 3,4-dihydroquinazolines in high yields.

A facile method for the synthesis of 3,1-benzooxazines from N-acyl-2-(alk-2-enyl)anilines

Electrophilic addition of HCl or Br2 to N-acyl-2-(alk-2-enyl)anilines is accompanied by intramolecular cyclization of these amides to give 3,1-benzooxazine hydrochlorides or hydrobromides in high yields.