367968-06-7

Basic information

• Product Name: (S)-Methyl 2-Bi-((Tert-Butoxycarbonyl)Amino)-5-Hydroxypentanoate
• Synonyms: (S)-Methyl 2-Bi-((Tert-Butoxycarbonyl)Amino)-5-Hydroxypentanoate;(S)-Methyl 2-Bi-((Tert-Butoxycarbonyl)Amino)-5-Hydroxypentanoate(WXC03587)
• CAS NO: 367968-06-7
• Molecular Formula: C16H29NO7
• Molecular Weight: 347.40396
• Mol File: 367968-06-7.mol
• Article Data: 16

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (S)-Methyl 2-Bi-((Tert-Butoxycarbonyl)Amino)-5-Hydroxypentanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-Methyl 2-Bi-((Tert-Butoxycarbonyl)Amino)-5-Hydroxypentanoate(367968-06-7)
• EPA Substance Registry System: (S)-Methyl 2-Bi-((Tert-Butoxycarbonyl)Amino)-5-Hydroxypentanoate(367968-06-7)

Safety Data

• Hazardous Substances Data: 367968-06-7(Hazardous Substances Data)

Usage

General Description

(S)-Methyl 2-Bi-((Tert-Butoxycarbonyl)Amino)-5-Hydroxypentanoate is a chemical compound with the molecular formula C15H27NO6. It is a derivative of the amino acid valine and belongs to the class of organic compounds known as esters. (S)-Methyl 2-Bi-((Tert-Butoxycarbonyl)Amino)-5-Hydroxypentanoate is commonly used in the synthesis of peptides and other bioactive molecules. It has also been studied for its potential pharmaceutical applications, particularly in the development of new drugs. Additionally, it is known for its role as a building block in the synthesis of complex organic molecules. Its specific chemical properties and potential applications make it a valuable compound in the fields of organic chemistry and pharmaceutical research.

Upstream product

• 192314-71-9 methyl (S)-2-N,N-di(tert-butoxycarbonyl)amino-5-oxopentanoate 
• 74-88-4 methyl iodide 
• 6525-53-7 L-glutamic acid dimethyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 
• 59279-60-6 dimethyl (2S)-2-[(tert-butoxycarbonyl)amino]pentanedioate 
• 23150-65-4 L-glutamic dimethyl ester hydrochloride 
• 56-86-0 L-glutamic acid 
• 206128-03-2 (S)-dimethyl 2-(bis(tert-butoxycarbonyl)amino)pentanedioate 

Downstream Products

• 13734-28-6 Boc-Lys-OH 

Relevant articles and documents

Synthesis of Imidazole and Histidine-Derived Cross-Linkers as Analogues of GOLD and Desmosine

Amino acid derivatives with a central cationic heterocyclic core (e.g., imidazolium) are biologically relevant cross-linkers of proteins and advanced glycation end (AGE) products. Here, imidazolium-containing cross-linkers were synthesized from imidazole or histidine by N-alkylation employing aspartate- and glutamate-derived mesylates as key step. Biological investigations were carried out to probe the biocompatibility of these compounds.

Synthesis and Biological Evaluation of a Library of AGE-Related Amino Acid Triazole Crosslinkers

Three N-Boc-protected amino acids, l-serine, l-aspartic, and l-glutamic acid, were either converted into their methyl azidoalkanoates or various alkynes via Bestmann-Ohira strategy or via reaction with propargylamine and propargyl bromide, respectively. The Cu-catalyzed click reaction provided a library of amino acid based triazoles, which were further N-methylated to triazolium iodides or deprotected and precipitated as free amino acid triazole dihydrochlorides. The biological properties of all derivatives were investigated by cytotoxicity assay (against L929 mouse fibroblasts) and broth microdilution method (E. coli ΔTolC and S. aureus). First results reveal complete inactivity for triazolium iodides with cell viabilities and microbial growths nearly 100 %, indicating them as possible analogs of advanced glycation endproducts (AGEs).

HERBICIDAL COMPOSITIONS

The present invention relates novel herbicidal combinations and their use in controlling plants or inhibiting plant growth. In particular, herbicidal combinations of the invention comprise at least one pyridazine derivative as defined herein, in combination with at least one futher herbicide that is an acetoclactase synthase (ALS) inhibitor.