36797-34-9

Upstream product

• 858208-06-7 C₁₇H₁₉NO₃S 
• 57775-06-1 2-(2-bromophenyl)-2-methylpropanenitrile 
• 1422148-87-5 N-acetyl-2-(2-bromophenyl)-2-methylpropanamide 
• 1422148-86-4 2-(2-bromophenyl)-2-methyl-N-tosylpropanamide 
• 173026-22-7 2-bromo-α,α-dimethylbenzeneacetamide 

Downstream Products

• 19155-24-9 3,3-dimethyloxindole 

Relevant academic research and scientific papers

Efficient copper-catalyzed intramolecular N-arylation for the synthesis of oxindoles

An efficient copper-catalyzed intramolecular N-arylation was performed by using substituted 2-(2-bromoaryl)acetamide with a small amount of Cu 2O and benzene-1,2-diamine as catalytic system under aerobic conditions, which provided good to excellent yields of oxindoles with tolerance of a wide variety of substrates.

Synthesis of oxindoles by palladium-catalyzed C-H bond amidation

Treatment of N-tosylphenylacetamide derivatives with cop-per(II) acetate in the presence of a catalytic amount of palladi-um(II) acetate affords 3,3-disubstituted oxindoles. The reaction proceeds through the intramolecular metallation of an aromatic C-H b