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36798-79-5

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36798-79-5 Usage

Description

Budralazine is an antihypertensive agent which is somewhat less potent than structurally related hydralazine, and reportedly produces less tachycardia.

Uses

Budralazine a new antihypertensive agent. Budralazine is a direct-acting vasodilator.

Manufacturing Process

A mixture of 2.0 g of 1-hydrazinophthalazine hydrochloride, 1.1 g of mesityl oxide (isoproplyideneacetone) and 100 ml of ethanol, was refluxed for 3 hours. The reaction mixture was concentrated in vacuo and the residue was dissolved in water. The water solution was neutralized with sodium bicarbonate, salted out and the product was extracted with benzene. The benzene layer was passed through a comparatively short column of alumina and the solvent was removed. The residue was crystallized from ether to give 0.7 g of 1-(1,3-dimethyl-2-butenylidene) hydrazinophthalazine, melting point 131°-132°C.

Brand name

BUTERAZINE

Therapeutic Function

Antihypertensive

Check Digit Verification of cas no

The CAS Registry Mumber 36798-79-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,6,7,9 and 8 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 36798-79:
(7*3)+(6*6)+(5*7)+(4*9)+(3*8)+(2*7)+(1*9)=175
175 % 10 = 5
So 36798-79-5 is a valid CAS Registry Number.
InChI:InChI=1/C14H16N4/c1-10(2)8-11(3)16-18-14-13-7-5-4-6-12(13)9-15-17-14/h4-9H,1-3H3,(H,17,18)/b16-11+

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36798-79-5Downstream Products

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