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Usage

Uses

Used in the Synthesis of Hybrid Materials:
3,5-Diaminobenzotrifluoride is used as a key intermediate in the synthesis of hybrid materials, specifically polyhedral oligomeric silsesquioxane (POSS) and fluorinated aromatic polyimide films. 3,5-Diaminobenzotrifluoride's unique structure and properties contribute to the development of these advanced materials, which exhibit improved mechanical, thermal, and chemical properties compared to their non-hybrid counterparts.
Used in the Electronics Industry:
In the electronics industry, 3,5-Diaminobenzotrifluoride is used as a precursor for the development of fluorinated aromatic polyimide films. These films are known for their excellent thermal stability, mechanical strength, and chemical resistance, making them ideal for applications such as flexible displays, photovoltaic devices, and microelectronic components.
Used in the Chemical Industry:
3,5-Diaminobenzotrifluoride is also utilized in the chemical industry for the synthesis of various specialty chemicals, including pharmaceuticals, agrochemicals, and dyes. Its unique reactivity and stability make it a valuable building block for the development of new molecules with specific properties and applications.
Used in the Research and Development of New Materials:
Due to its unique structure and properties, 3,5-Diaminobenzotrifluoride is often used in research and development efforts to create new materials with tailored properties. Scientists and researchers can exploit the compound's reactivity to design and synthesize novel materials with potential applications in various industries, such as aerospace, automotive, and energy.

InChI:InChI=1/C5H3F3N2OS/c6-5(7,8)2-1-3(11)10-4(12)9-2/h1H,(H2,9,10,11,12)

Upstream product

• 393-75-9 4-chloro-3,5-dinitrobenzotrifluoride 
• 401-99-0 3,5-dinitrobenzotrifluoride 

Downstream Products

• 349-61-1 N,N'-(5-(trifluoromethyl)-1,3-phenyl)bisacetamide 
• 782-80-9 5-Trifluormethylphenyl-1,3-diisocyanat 
• 455279-96-6 N-(3-amino-5-(trifluoromethyl)phenyl)acetamide 
• 535-87-5 3.5-diaminobenzoic acid 
• 1949-55-9 methyl 3,5-diaminobenzoate 
• 702672-62-6 N₂-(3-amino-5-(trifluoromethyl)phenyl)-5-bromo-N₄-(2-(1H-imidazol-4-yl)ethyl)-2,4-pyrimidinediamine 
• 702674-91-7 N-(3-((5-bromo-4-((2-(1H-imidazol-4-yl)ethyl)amino)-2-pyrimidinyl)amino)-5-(trifluoromethyl)phenyl)-ethanimidamide 
• 863675-98-3 N-(3-amino-5-(trifluoromethyl)phenyl)-2,2,2-trifluoroacetamide 
• 795307-83-4 (3-amino-5-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester 
• 873056-09-8 N-[3-amino-5-(trifluoromethyl)phenyl]methanesulfonamide 
• 1532526-02-5 N¹,N^1'-(5-(trifluoromethyl)-1,3-phenylene)bis(N²-mesitylbenzene-1,2-diamine) 
• 1610038-13-5 2-(3-amino-5-(trifluoromethyl)phenyl)isoindoline-1,3-dione 
• 1579998-96-1 (E)-2-(3-((3,5-di(pyrrolidine-1-carbonyl)phenyl)diazenyl)-5-(trifluoromethyl)phenyl)-isoindoline-1,3-dione 
• 1579999-01-1 (E)-(5-((3-amino-5-(trifluoromethyl)phenyl)diazenyl)-1,3-phenylene)bis(pyrrolidin-1-ylmethanone) 

Relevant academic research and scientific papers

HETEROARYLPHENYLUREA DERIVATIVE

The present invention provides a compound represented by the formula (1): wherein R 1 , R 2 and R 5 are each independently selected from a hydrogen atom, a halogen atom, a C 1 -C 6 alkyl is substituted with a halogen atom and the like; R 3 and R 4 are each independently selected from a hydrogen atom, a halogen atom, a substituted C 1 -C 6 alkyl group and the like; R 6 and R 7 are each independently selected from a hydrogen atom and a halogen atom; Z 1 and Z 2 are each independently selected from a hydrogen atom, a hydroxyl group and -O(CHR 11 )OC(=O)R 12 ; Q is a group of the formula: (wherein G 1 is C-Y 2 or N; a ring A is a benzene ring or a 5- to 6-membered unsaturated heterocycle) a pharmaceutically acceptable salt thereof or a prodrug thereof.

Photochemical reactivity of trifluoromethyl aromatic amines: The example of 3,5-diamino-trifluoromethyl-benzene (3,5-DABTF)

This work presents the application of an on-line photoreactor to the detection of 3,5-diamino-trifluoromethyl-benzene (3,5-DABTF) in aqueous solutions. When irradiated at 310 nm, this compound is defluorinated to 3,5-diaminobenzoic acid by a nucleophilic substitution of the fluoride by water. Concomitantly, defluorination intermediates polymerize through amide bonds to give dark-colored compounds. We take advantage of the photocatalyzed defluorination and the subsequent decrease in pH to develop an original and specific photoreactor. Continuous recording of pH and temperature in the outlet of the reactor by a dual electrode gives us an opportunity to optimize the system. In the photoreactor, 3,5-DABTF is immediately and totally transformed as attested by the rapid drop of the flowing solution pH from 6.2 to 3.2 and the chromatographic analysis of the outgoing solutions. The detection remains effective from 1 to 1000 parts per million.

Preparation of 3,5-diaminobenzotrifluoride

3,5-Diaminobenzotrifluoride can be produced, in a single step, by reacting 4-chloro-3,5-dinitrobenzotrifluoride, in methanol, with hydrogen gas, in the presence of magnesium oxide, and in the presence of a catalyst comprising palladium on a carbon support.

Process for the preparation of 3,5-diaminobenzotrifluoride

3,5-Diaminobenzotrifluoride is prepared by reaction of 4-chloro-3,5-dinitrobenzotrifluoride with sodium formate in acetic acid, in the presence of sodium acetate and palladium on charcoal.

Preparation of 3,5-diamino benzotrifluoride

3,5-Diaminobenzotrifluoride can be produced, in a single step, by reacting 4-chloro-3,5-dinitro benzotrifluoride in a suitable solvent, with hydrogen gas, in the presence of a catalyst comprising palladium on a suitable carrier, and in the presence of a suitable base.