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Declorogriseofulvin is a chemical compound derived from griseofulvin, an antibiotic used to treat fungal infections. It is formed by the removal of one chlorine atom from griseofulvin, resulting in a slightly different chemical structure. This alteration may affect its pharmacological properties, such as potency, solubility, or metabolic stability. Declorogriseofulvin is of interest in pharmaceutical research as it could potentially offer advantages over the parent compound, such as reduced side effects or improved efficacy. However, it is important to note that dechlorogriseofulvin is not a commercially available drug and its use is primarily limited to scientific investigation.

3680-32-8

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3680-32-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 3680-32-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,6,8 and 0 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 3680-32:
(6*3)+(5*6)+(4*8)+(3*0)+(2*3)+(1*2)=88
88 % 10 = 8
So 3680-32-8 is a valid CAS Registry Number.

3680-32-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 7-Dechloro Griseofulvin

1.2 Other means of identification

Product number -
Other names 2',4,6-Trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cycloh ex[2]ene]-3,4'-dione

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:3680-32-8 SDS

3680-32-8Downstream Products

3680-32-8Relevant academic research and scientific papers

Photodegradation of antimycotic drugs. 4. Communication: Photodegradation of flucytosine and griseofulvin

Thoma,Kuebler,Reimann

, p. 455 - 463 (2007/10/03)

The antimycotic drug substances flucytosine and griseofulvin are degraded under the influence of light. A liquid chromatography-mass spectrometry system helped us to elucidate some of the photodegradation pathways. 5-Fluorouracil is one of the photodegradation products of flucytosine in aqueous solution. The photodegradation of griseofulvin in solutions is mainly influenced by the solvent. The photodegradation product deschlorgriseofulvin could be detected in aqueous solution as well as in ethanolic and methanolic solution. Two photodegradation products found in ethanolic solution could, however, not be detected in methanolic or aqueous solution. Storage instructions of the pharmocopoeias are quite surprising. The US and the German pharmacopoeia recommend light protected storage for flucytosine but not for griseofulvin although griseofulvin is photodegraded more rapidly than flucytosine.

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