36809-05-9

Upstream product

• 40638-92-4 1,1-dideuterio-2-phenylethanol 
• 98-59-9 p-toluenesulfonyl chloride 
• 103-82-2 phenylacetic acid 
• 101-41-7 benzeneacetic acid methyl ester 

Downstream Products

• 66997-32-8 2-phenylethyldimethylamine-1,1-d2 
• 66997-34-0 2-phenylethyldimethylamine-1,1-d2 oxide 
• 86823-61-2 C₆H₅CH₂C(⁽²⁾H)2W(CO)3(C₅H₅) 

Relevant academic research and scientific papers

Secondary α hydrogen-deuterium kinetic isotope effects in the syn-elimination reaction of 2-phenylethyldimethylamine oxide

The secondary α-deuterium kinetic isotope effect has been measured for the thermal reaction of 2-phenylethyldimethylamine oxide in 90 mol percent DMSO-H2O at 60.0 deg C.A large secondary α-deuterium isotope effect of 1.158 per α-D was found, which indicates significant C-N bond rupture and very little double bond formation at the transition state for this concerted syn-elimination process.The observed large normal value for (kH/kD)α is discussed in terms of the use of secondary α-D isotope effects for the determination of stereochemistry for a concerted elimination process.Various isotope effects found for the syn elimination of the above amine oxide and those for the anti elimination of 2-arylethyltrimethylammonium salts with ethoxide are considered with respect to the relative transition state structures for syn- and anti-elimination reactions.

Substituents Effects. XVII. Rearrangement in the Acetolysis of 2-Arylethyl Tosylates

The label scrambling within the ethylene chain of the final acetolysis products was determined for a series of α-D2 labeled 2-arylethyl tosylates using proton NMR spectroscopy and the kΔ/ks values were derived from the scr