36841-47-1 Usage
Uses
Used in Pharmaceutical Industry:
(2-P-TOLYL-OXAZOL-4-YL)-METHANOL is used as a building block for the synthesis of various pharmaceuticals, leveraging its unique molecular structure and diverse reactivity to create new and effective drugs.
Used in Agrochemical Industry:
(2-P-TOLYL-OXAZOL-4-YL)-METHANOL is used as a building block for the synthesis of various agrochemicals, contributing to the development of innovative and efficient products for agricultural applications.
Used in Drug Development:
(2-P-TOLYL-OXAZOL-4-YL)-METHANOL is used as a potentially valuable ingredient in drug development due to its antifungal and anti-inflammatory properties, offering new therapeutic opportunities for various medical conditions.
Used in Organic Chemistry Research:
(2-P-TOLYL-OXAZOL-4-YL)-METHANOL is used as a versatile compound in organic chemistry research, enabling the exploration of new chemical reactions and the development of novel synthetic pathways.
Check Digit Verification of cas no
The CAS Registry Mumber 36841-47-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,6,8,4 and 1 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 36841-47:
(7*3)+(6*6)+(5*8)+(4*4)+(3*1)+(2*4)+(1*7)=131
131 % 10 = 1
So 36841-47-1 is a valid CAS Registry Number.
36841-47-1Relevant academic research and scientific papers
Discovery of the disubstituted oxazole analogues as a novel class anti-tuberculotic agents against MDR- and XDR-MTB
Li, Dongsheng,Gao, Nana,Zhu, Ningyu,Lin, Yuan,Li, Yan,Chen, Minghua,You, Xuefu,Lu, Yu,Wan, Kanglin,Jiang, Jian-Dong,Jiang, Wei,Si, Shuyi
supporting information, p. 5178 - 5181 (2015/11/09)
A high-throughput screening effort on 45,000 compounds resulted in the discovery of a disubstituted oxazole as a new structural class inhibitor of Mycobacterium tuberculosis (Mtb). In order to improve the activity and investigate the SAR of this scaffold, a series of disubstituted azole analogues have been designed and synthesized. The newly synthesized compounds 1a-y were evaluated for their in vitro anti-TB activity versus replicating, multi- and extensive drug resistant Mtb strains. All the compounds, except 1o, 1p and 1q, showed potent anti-TB activity with MIC of 1-64 mg/L. The test of broad spectrum panel revealed that this series are specific to Mtb. The cytotoxicity assessment indicated that the compounds were not cytotoxic against HEK 293 cells. The compounds could have a novel mechanism to anti-Mtb as they can inhibit drug sensitive and drug resistant Mtb.
