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(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-Methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyramid is a complex organic compound characterized by its unique molecular structure. It is a chiral molecule with two asymmetric carbon atoms, denoted as R-configuration at both the 2nd and 3rd positions. (2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-Methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyraMide features a 2,5-difluorophenyl group, a hydroxyl group, a methyl group, and a 1,2,4-triazol-1-yl thiobutyramide moiety. Its intricate structure suggests potential applications in various fields, particularly in the pharmaceutical industry.

368421-58-3

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368421-58-3 Usage

Uses

Used in Pharmaceutical Industry:
(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-Methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyramid is used as an intermediate in the synthesis of Isavuconazole (I777830), a triazole-based antifungal agent. Isavuconazole is effective for the treatment of invasive fungal infections, making (2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-Methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyraMide a crucial component in the development of life-saving medications.
As an intermediate in the synthesis of Isavuconazole, (2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-Methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyramid plays a significant role in the pharmaceutical industry. Its unique structure and properties contribute to the development of potent antifungal drugs that can combat a wide range of invasive fungal infections, providing a valuable treatment option for patients in need.

Check Digit Verification of cas no

The CAS Registry Mumber 368421-58-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,6,8,4,2 and 1 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 368421-58:
(8*3)+(7*6)+(6*8)+(5*4)+(4*2)+(3*1)+(2*5)+(1*8)=163
163 % 10 = 3
So 368421-58-3 is a valid CAS Registry Number.

368421-58-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name (2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyramide

1.2 Other means of identification

Product number -
Other names Isavuconazole intermediate 8

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:368421-58-3 SDS

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