368424-85-5Relevant academic research and scientific papers
Cross-metathesis of C-glycosides and peptides
Bruechner, Peter,Koch, David,Voigtmann, Ulrike,Blechert, Siegfried
, p. 2757 - 2769 (2008/02/12)
Peptides bearing an acryloyl residue at their N-terminus were coupled with various C-glycosides in an equimolar ratio via cross-metathesis. The newly formed olefin was obtained with high E/Z selectivity in satisfying to high yields with low homodimerizati
Rapid microwave-assisted deprotection of N-Cbz and N-Bn derivatives
Daga, Maria Caterina,Taddei, Maurizio,Varchi, Greta
, p. 5191 - 5194 (2007/10/03)
Catalytic-transfer hydrogenation in iso-propanol under microwave irradiation has been performed to rapidly deprotect N-Cbz and N-Bn derivatives. The method is particularly suitable for the synthesis of short peptides and can also be carried out on supported molecules. The rapid cleavage of chiral molecules derived from (S)-1-phenylethylamine can be very useful for asymmetric synthesis of nitrogen containing compounds.
