36845-90-6Relevant academic research and scientific papers
Conversion of N-aromatic amides to O-aromatic esters
Glatzhofer, Daniel T.,Roy, Raymond R.,Cossey, Kimberly N.
, p. 2349 - 2352 (2007/10/03)
(Matrix Presented) N-Aromatic secondary amides can be transformed into O-aromatic esters in high yield via N-nitrosamide intermediates. The amides can be generated in situ from the corresponding aromatic amines or nitro compounds, and phenols can easily be made from the esters. The reaction can be modified by addition of methyl methacrylate or toluene at 0 °C to give polymerization or deamination, respectively. The rearrangement mechanism may involve radical formation and recombination.
