36848-19-8

Upstream product

• 101352-53-8 2-phenyl-5-phenylazo-pyrimidine-4,6-diyldiamine 
• 6017-21-6 benzeneazomalononitrile 
• 62-53-3 aniline 
• 52644-22-1 4,6-diamino-2-phenylpyrimidine 

Relevant academic research and scientific papers

Synthesis and antiviral and antitumor activities of 2H-[1,2,3]triazolo[4,5-d]pyrimidines and 1H-, 2H-, and 3H-[1,2,3] triazolo [4,5-d]pyrimidin-5(4H)-one-7(6H)-thiones

This paper describes a facile synthesis of 2-aryl-2H-[1,2,3]triazolo-[4,5-d]pyrimidine-5,7(4H,6H)-diones (3a-o) and 7-amino-2-aryl-5-phenyl-2H-[1,2,3]triazolo[4,5-d]pyrimidines (6a-e) prepared by oxidative cyclization of 6-amino-5-arylazopyrimidine-2,4(1H-3H)-diones (2a-o) and 4,6-diamino-5-arylazo-2-phenylpyrimidines (5a-e) with CUSO4, respectively, and a reliable thionation of [1,2,3]triazolo[4,5-d]pyrimidine-5,7(4H,6H)-diones (3a,e,f, 7a,b and 9) accomplished by the reaction with phosphorous pentasulfide or Lawesson's reagent as well as evaluation of their antiviral and antitumor activities in vitro.