36855-09-1

Basic information

• Product Name: 5-(2-Thienyl)-1H-tetrazole-1-acetic acid
• Synonyms: 5-(2-Thienyl)-1H-tetrazole-1-acetic acid
• CAS NO: 36855-09-1
• Molecular Formula: C7H6 N4 O2 S
• Molecular Weight: 0
• Mol File: 36855-09-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 484.4°Cat760mmHg
• Flash Point: 246.8°C
• Appearance: /
• Density: 1.71g/cm³
• Vapor Pressure: 3.39E-10mmHg at 25°C
• Refractive Index: 1.801
• CAS DataBase Reference: 5-(2-Thienyl)-1H-tetrazole-1-acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(2-Thienyl)-1H-tetrazole-1-acetic acid(36855-09-1)
• EPA Substance Registry System: 5-(2-Thienyl)-1H-tetrazole-1-acetic acid(36855-09-1)

Safety Data

• Hazardous Substances Data: 36855-09-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C7H6N4O2S/c12-6(13)4-11-7(8-9-10-11)5-2-1-3-14-5/h1-3H,4H2,(H,12,13)

Upstream product

• 36852-96-7 (5-thiophen-2-yl-tetrazol-1-yl)-acetic acid ethyl ester 
• 59541-58-1 5-(thiophen-2-yl)-1H-tetrazole 

Relevant articles and documents

TETRAZOLEACETIC ACID DERIVATIVES AND USE FOR ALDOSE REDUCTASE INHIBITORY ACTIVITY

A tetrazoleacetic acid derivative represented by the following general formula (I): [in Formula (I), R1 represents a hydrogen atom or an alkyl group; R2 represents a hydrogen atom, an alkyl group, an aralkyl group, a halogen atom, a haloalkyl group, a hydroxyl group, an alkoxy group, an alkoxyalkyl group, an amino group, an aryl group, an alkyl or aryl thio group, an alkyl or aryl carbonylamino group, an alkyl or aryl sulfonylamino group, an alkyl or aryl aminosulfonyl group, an alkyl or aryl sulfonyl group or an alkyl or aryl sulfinyl group; and X represents -O- or -S-] except for [5-(2-thienyl)tetrazol-1-yl] acetic acid, [5-(2-furyl)tetrazol-1-yl] acetic acid and ethyl esters thereof, or a salt thereof shows excellent aldose reductase inhibitory activity, has low toxicity to organisms and is quite effective as an essential component of a preventive medicine and/or remedy for diabetic complications.