Strophanthidin 3-O-β-D-glucopyranoside is a naturally occurring cardiac glycoside found in the seeds of the Strophanthus kombé plant. It is a secondary metabolite that exhibits potent cardiotonic effects, primarily by inhibiting the Na+/K+-ATPase enzyme, which plays a crucial role in maintaining the electrochemical gradient across cell membranes. This inhibition leads to an increase in intracellular calcium levels, thereby enhancing myocardial contractility. The presence of a β-D-glucopyranoside moiety in its structure is significant as it influences the compound's solubility, bioavailability, and pharmacokinetics. Strophanthidin 3-O-β-D-glucopyranoside has been traditionally used in the treatment of heart failure and certain cardiac arrhythmias, although its use has been largely replaced by more modern medications due to its narrow therapeutic index and potential for toxicity.
3686-97-3
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Basic information
- Product Name: strophanthidin 3-O-β-D-glucopyranoside
- Synonyms:
- CAS NO:3686-97-3
- Molecular Formula:
- Molecular Weight: 566.646
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: strophanthidin 3-O-β-D-glucopyranoside(CAS DataBase Reference)
- NIST Chemistry Reference: strophanthidin 3-O-β-D-glucopyranoside(3686-97-3)
- EPA Substance Registry System: strophanthidin 3-O-β-D-glucopyranoside(3686-97-3)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 3686-97-3(Hazardous Substances Data)
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Check Digit Verification of cas no
The CAS Registry Mumber 3686-97-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,6,8 and 6 respectively; the second part has 2 digits, 9 and 7 respectively.Calculate Digit Verification of CAS Registry Number 3686-97:
(6*3)+(5*6)+(4*8)+(3*6)+(2*9)+(1*7)=123
123 % 10 = 3
So 3686-97-3 is a valid CAS Registry Number.
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strophanthidin 3-O-β-D-glucopyranoside
