36881-97-7Relevant articles and documents
POTENTIAL CEREBRAL STIMULANTS: ESTERS OF 2-DIMETHYLAMINOETHANOL WITH SOME LIPOPHILIC CARBOXYLIC ACIDS
Protiva, Miroslav,Valenta, Vladimir,Kopicova, Zdenka,Lukac, Juraj,Holubek, Jiri,Krejci, Ivan
, p. 1278 - 1289 (2007/10/02)
2-Dimethylaminoethyl esters of 2,2-dimethylpropanoic, heptanoic, octanoic, decanoic, hexadecanoic, cyclopentylacetic, cycloheptylacetic, 2-cyclopenthylhexanoic, (4-chlorophenoxy)fumaric, and 2-(4-chlorophenoxy)succinic acid were prepared by reactions of the acid chlorides with 2-dimethylaminoethanol and were transformed to crystalline salts for pharmacological testing.The ester IX (hydrogen fumarate VUFB-14005) was found to antagonize significantly halothan amnesia in rats and the ester X (hydrogen fumarate VUFB-14004) proved to be an anticholinergic spasmolytic agent.