368883-74-3

Upstream product

• 368883-73-2 4-(3-Chlorophenyl)-6-methoxy-1,2-dihydronaphthalene 
• 637-69-4 4-Methoxystyrene 
• 2039-85-2 3-Chlorostyrene 

Relevant academic research and scientific papers

Visible-Light-Mediated [4+2] Cycloaddition of Styrenes: Synthesis of Tetralin Derivatives

We report a formal [4+2] cycloaddition reaction of styrenes under visible-light catalysis. Two styrene molecules with different electronic or steric properties were found to react with each other in good yield and excellent chemo- and regioselectivity. This reaction provides direct access to polysubstituted tetralin scaffolds from readily available styrenes. Sophisticated tricyclic and tetracyclic tetralin analogues were prepared in high yield and up to 20/1 diasteroselectivity from cyclic substrates.

1,2,3,4-Tetrahydronaphthalene compound and preparation method and application thereof

The invention discloses 1,2,3,4-tetrahydronaphthalene compound and a preparation method and application thereof. The 1,2,3,4-tetrahydronaphthalene compound has a molecular structural formula shown asformula (I) that is shown in the description. The prepar

5- substituted tetralones as inhibitors of ras farnesyl trransferase

The present invention provides novel 5-substituted tetralones of Formulas (I), (II), (III) and (IV) and pharmaceutically acceptable salts, esters, amides, and prodrugs thereof, which are useful for treating and preventing uncontrolled or abnormal proliferation of tissues, such as cancer, atherosclerosis, restenosis, and psoriasis. Specifically, the present invention relates to compounds that inhibit the farnesyl transferase enzyme.