368889-99-0Relevant articles and documents
The first example of a new type of acyclic, achiral nucleoside analogue: 1-[3-hydroxy-2-(hydroxymethyl)prop-1-enyl]thymine
Pedersen,Boesen,Eldrup,Kiaer,Madsen,Henriksen,Dahl
, p. 1656 - 1661 (2001)
Various preparative routes to 1-(dihydroxyalk-1-enyl)thymines, which are acyclic, achiral nucleoside analogues, have been examined, and a successful synthesis of 1-[3-hydroxy-2-(hydroxymethyl)prop-1-enyl]thymine (1, B = T) has been devised.