36894-28-7

Basic information

• Product Name: N-(4-nitrophenyl)morpholine-4-carboxamide
• Synonyms: 4-morpholinecarboxamide, N-(4-nitrophenyl)-
• CAS NO: 36894-28-7
• Molecular Formula: C₁₁H₁₃N₃O₄
• Molecular Weight: 251.2386
• Mol File: 36894-28-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 510.7°C at 760 mmHg
• Flash Point: 262.7°C
• Density: 1.403g/cm³
• Vapor Pressure: 1.51E-10mmHg at 25°C
• Refractive Index: 1.632
• CAS DataBase Reference: N-(4-nitrophenyl)morpholine-4-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-nitrophenyl)morpholine-4-carboxamide(36894-28-7)
• EPA Substance Registry System: N-(4-nitrophenyl)morpholine-4-carboxamide(36894-28-7)

Safety Data

• Hazardous Substances Data: 36894-28-7(Hazardous Substances Data)

Upstream product

• 30543-38-5 N-phenyl-1-morpholinecarbimidoyl chloride 
• 110-91-8 morpholine 
• 1613-76-9 4-nitrobenzohydroxamic acid 
• 2666-74-2 4-nitrophenylisocyanide dichloride 

Relevant articles and documents

Bromodimethylsulfonium bromide (BDMS)-mediated Lossen rearrangement: Synthesis of unsymmetrical ureas

Bromodimethylsulfonium bromide (BDMS) was found to be a very efficient reagent for Lossen rearrangement of hydroxamic acids to the corresponding isocyanates which were subsequently trapped in situ with various amines to afford unsymmetrical ureas in good to excellent yields (64-89%). The protocol is experimentally simple, mild, and represents valuable alternative to the existing methods for in situ activation of hydroxamic acids promoting Lossen rearrangement.