36901-09-4

Basic information

• Product Name: 5-ethyl-4,5-dimethyl-3-phenylfuran-2(5H)-one
• Synonyms: 5-ethyl-4,5-dimethyl-3-phenylfuran-2(5H)-one
• CAS NO: 36901-09-4
• Molecular Weight: 216.28
• Mol File: 36901-09-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-ethyl-4,5-dimethyl-3-phenylfuran-2(5H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-ethyl-4,5-dimethyl-3-phenylfuran-2(5H)-one(36901-09-4)
• EPA Substance Registry System: 5-ethyl-4,5-dimethyl-3-phenylfuran-2(5H)-one(36901-09-4)

Safety Data

• Hazardous Substances Data: 36901-09-4(Hazardous Substances Data)

Upstream product

• 109916-61-2 3-hydroxy-3-methyl-pentan-2-one 
• 140-29-4 phenylacetonitrile 

Relevant articles and documents

Copper-Catalyzed [2 + 3] Cyclization of α-Hydroxyl Ketones and Arylacetonitriles: Access to Multisubstituted Butenolides and Oxazoles

A copper-catalyzed [2 + 3] formal cyclization reaction between α-hydroxyl ketones and arylacetonitriles has been developed. The reaction outcome was ultimately dependent on the structure of the α-hydroxy ketones employed. Tertiary α-hydroxy ketones gave 3,4,5,5-tetrasubstituted butenolides as the sole products, while secondary α-hydroxy ketones furnished 2,4,5-trisubstituted oxazoles selectively. This method has many advantages, such as the use of easily available substrates, broad substrate scope, good functional tolerance, and milder reaction conditions.